ArticlePloS one2021
Association between lactate/albumin ratio and all-cause mortality in patients with acute respiratory failure: A retrospective analysis.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Association between lactate-to-albumin ratio and 28-day all-cause mortality in critically ill patients with chronic kidney disease: A retrospective cohort study from the Medical Information Mart for Intensive Care IV database.The Journal of international medical research · 2026Article
- Association between albumin-bilirubin score and all-cause mortality in patients with acute respiratory failure: a cohort study based on the MIMIC-IV database.Journal of thoracic disease · 2026Article
- Mechanistic Studies of Lactate in Heart Failure: From Metabolic Biomarker to Therapeutic Target.Reviews in cardiovascular medicine · 2026Review
- Article
- Association between albumin-corrected anion gap and in-hospital mortality in ICU patients with lung cancer: a retrospective cohort study based on the MIMIC database.Journal of thoracic disease · 2026Article
- Evaluating the predictive power of lactate-to-albumin ratio on 30-day mortality among sepsis patients: a retrospective cohort study.BMC infectious diseases · 2026Article
- Early Peri-Admission Lactate-to-Albumin (LAR), C-Reactive Protein-to-Albumin (CAR), and Procalcitonin-to-Albumin (PAR) Ratios and ICU Mortality in a Tertiary Cardiac ICU.Journal of clinical medicine · 2026Article
- Prognostic utility of the lactate-to-albumin ratio for predicting 28-day all-cause mortality in critically ill cases with acute sepsis: A retrospective study on the basis of MIMIC-IV critical care database.Journal of medical biochemistry · 2026Article
- Early prognostic value of the lactate-to-albumin ratio in severe acute pancreatitis with acute respiratory distress syndrome.Frontiers in medicine · 2026Article
- Article
- Lactate-to-albumin ratio improves prediction of perioperative mortality in lung transplant patients.Frontiers in medicine · 2026Article
- Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis.Frontiers in medicine · 2026Article
- Prognostic significance of lactate/albumin ratio in respiratory failure and sepsis.Annals of medicine · 2025Article
- Prognostic value of lactate-to-hemoglobin ratio in nontraumatic critically ill patients presenting to the emergency department: a retrospective cohort study.BMC emergency medicine · 2025Observational
- Lactate-to-albumin ratio as an independent predictor of 28-day ICU mortality in patients with hypertension: a retrospective cohort study.Scientific reports · 2025Article
- Association of the Lactate/Albumin Ratio with Mortality and Hypovolemia in Critically Ill Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- A prediction model for 30-day mortality in patients with ARDS admitted to the intensive care unit.European journal of medical research · 2025Article
- The role of the Lactate-to-Albumin ratio in predicting ICU admission and mortality in patients with UGIB presenting to the ED: a prospective observational study.BMC emergency medicine · 2025Observational
- Lactate to albumin ratio as a determinant of intensive care unit admission and mortality in hospitalized patients with community-acquired pneumonia.BMC pulmonary medicine · 2025Article
- Lactate to albumin ratio as a prognosis predictor in gastrointestinal bleeding in the emergency department.Internal and emergency medicine · 2025Article
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4 authors.
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Abstract
Previous studies have shown that lactate/albumin ratio (LAR) can be used as a prognostic biomarker to independently predict the mortality of sepsis and severe heart failure. However, the role of LAR as an independent prognostic factor in all-cause mortality in patients with acute respiratory failure (ARF) remains to be clarified. Therefore, we retrospectively analyzed 2170 patients with ARF in Medical Information Mart for Intensive Care Database III from 2001 to 2012. By drawing the receiver operating characteristic curve, LAR shows a better predictive value in predicting the 30-day mortality of ARF patients (AUC: 0.646), which is higher than that of albumin (AUC: 0.631) or lactate (AUC: 0.616) alone, and even higher than SOFA score(AUC: 0.642). COX regression analysis and Kaplan-Meier curve objectively and intuitively show that high LAR is a risk factor for patients with ARF, which is positively correlated with all-cause mortality. As an easy-to-obtain and objective biomarker, LAR deserves further verification by multi-center prospective studies.
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