ArticleJournal of neurophysiology2021
Within-cycle instantaneous frequency profiles report oscillatory waveform dynamics.
Article in Journal of neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain.Neuron · 2025Article
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- Burst estimation through atomic decomposition (BEAD): A toolbox to find oscillatory bursts in brain signals.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- NovelImaging neuroscience (Cambridge, Mass.) · 2025Article
- Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal.bioRxiv : the preprint server for biology · 2024Article
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- Novel Cyclic Homogeneous Oscillation Detection Method for High Accuracy and Specific Characterization of Neural Dynamics.bioRxiv : the preprint server for biology · 2024Article
- Different Methods to Estimate the Phase of Neural Rhythms Agree But Only During Times of Low Uncertainty.eNeuro · 2023Article
- The medial septum controls hippocampal supra-theta oscillations.Nature communications · 2023Article
- The association between working memory precision and the nonlinear dynamics of frontal and parieto-occipital EEG activity.Scientific reports · 2023Article
- Different methods to estimate the phase of neural rhythms agree, but only during times of low uncertainty.bioRxiv : the preprint server for biology · 2023Article
- Review
- The potential of convolutional neural networks for identifying neural states based on electrophysiological signals: experiments on synthetic and real patient data.Frontiers in human neuroscience · 2023Article
- A review of critical brain oscillations in depression and the efficacy of transcranial magnetic stimulation treatment.Frontiers in psychiatry · 2023Review
- Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in aging mice.Cell reports · 2022Article
- Running speed and REM sleep control two distinct modes of rapid interhemispheric communication.Cell reports · 2022Article
- Detection and analysis of cortical beta bursts in developmental EEG data.Developmental cognitive neuroscience · 2022Article
- Understanding Harmonic Structures Through Instantaneous Frequency.IEEE open journal of signal processing · 2022Article
- Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
Abstract
The nonsinusoidal waveform is emerging as an important feature of neuronal oscillations. However, the role of single-cycle shape dynamics in rapidly unfolding brain activity remains unclear. Here, we develop an analytical framework that isolates oscillatory signals from time series using masked empirical mode decomposition to quantify dynamical changes in the shape of individual cycles (along with amplitude, frequency, and phase) with instantaneous frequency. We show how phase-alignment, a process of projecting cycles into a regularly sampled phase grid space, makes it possible to compare cycles of different durations and shapes. "Normalized shapes" can then be constructed with high temporal detail while accounting for differences in both duration and amplitude. We find that the instantaneous frequency tracks nonsinusoidal shapes in both simulated and real data. Notably, in local field potential recordings of mouse hippocampal CA1, we find that theta oscillations have a stereotyped slow-descending slope in the cycle-wise average yet exhibit high variability on a cycle-by-cycle basis. We show how principal component analysis allows identification of motifs of theta cycle waveform that have distinct associations to cycle amplitude, cycle duration, and animal movement speed. By allowing investigation into oscillation shape at high temporal resolution, this analytical framework will open new lines of inquiry into how neuronal oscillations support moment-by-moment information processing and integration in brain networks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.