Evidence map›Paper›PMID 34406874›Full record

ArticleJournal of neurophysiology2021

Hippocampal β2-GABA

Alexander G Figueroa, Claudia Benkwitz, Gabe Surges, Nicholas Kunz, Gregg E Homanics, Robert A Pearce

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alexander G FigueroaDepartment of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Claudia BenkwitzDepartment of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Gabe SurgesDepartment of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Nicholas KunzDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Gregg E HomanicsDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0003-3641-8153
Robert A PearceDepartment of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0002-1516-6260
University of Wisconsin–Madison · USUniversity of Pittsburgh · US

Funding

Role of noncoding RNA in alcohol actionU01AA020889 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sean P Farris, Gregg E. Homanics · 2011 to 2026
$7.1M
Ethanol Mechanisms in GABAAR Gene Targeted MiceR37AA010422 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOMANICS, GREGG E. · 2010 to 2019
$4.4M
ETHANOL MECHANISMS IN GABAAR GENE TARGETED MICER01AA010422 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOMANICS, GREGG E. · 1995 to 2008
$3.1M
LNCRNA REGULATION OF GENE EXPRESSION & BEHAVIORR01AA030257 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sean P Farris · 2022 to 2026
$2.8M
Anesthetic Suppression of Memory through disinhibitory circuits in HippocampusR01GM118801 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PEARCE, ROBERT A · 2016 to 2019
$1.9M
NIAAA NIH HHS R01 AA010422NIAAA NIH HHS R01 AA030257NIAAA NIH HHS R37 AA010422NIAAA NIH HHS U01 AA020889NIGMS NIH HHS R01 GM118801
6 · The paper itself

Abstract

The general anesthetic etomidate, which acts through γ-aminobutyric acid type A (GABA

Indexed as

Anesthetics, IntravenousAnimalsEtomidateHippocampusLong-Term PotentiationMiceMice, Inbred C57BLMice, TransgenicNeural InhibitionPyramidal CellsReceptors, GABA-AAnesthetics, IntravenousEtomidateGabrb2 protein, mouseGabrb3 protein, mouseReceptors, GABA-AetomidateGABAA receptorsgeneral anesthesialearning and memory

Identifiers

PMID34406874
PMCPMC8560413
OpenAlexW3194273761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.