Evidence map›Paper›PMID 34406860›Full record

ArticleJournal of virology2021

The Borna Disease Virus 2 (BoDV-2) Nucleoprotein Is a Conspecific Protein That Enhances BoDV-1 RNA-Dependent RNA Polymerase Activity.

Takehiro Kanda, Masayuki Horie, Yumiko Komatsu, Keizo Tomonaga

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Takehiro KandaLaboratory of RNA Viruses, Department of Virus Research, Institution for Frontier Life and Medical Science, Kyoto University, Kyoto, Japan.
Masayuki HorieLaboratory of RNA Viruses, Department of Virus Research, Institution for Frontier Life and Medical Science, Kyoto University, Kyoto, Japan.ORCID 0000-0003-4682-7698
Yumiko KomatsuLaboratory of RNA Viruses, Department of Virus Research, Institution for Frontier Life and Medical Science, Kyoto University, Kyoto, Japan.
Keizo TomonagaLaboratory of RNA Viruses, Department of Virus Research, Institution for Frontier Life and Medical Science, Kyoto University, Kyoto, Japan.ORCID 0000-0003-0405-7103
Kyoto University · JP

Funding

Japan Society for the Promotion of Science (JSPS) 18K19443Japan Society for the Promotion of Science (JSPS) 19J23468Japan Society for the Promotion of Science (JSPS) 19K22530Japan Society for the Promotion of Science (JSPS) 20H05682Japan Society for the Promotion of Science (JSPS) 21H01199Ministry of Education, Culture, Sports, Science and Technology (MEXT) 16H06429Ministry of Education, Culture, Sports, Science and Technology (MEXT) 16H06430Ministry of Education, Culture, Sports, Science and Technology (MEXT) 16K21723
6 · The paper itself

Abstract

An RNA virus-based episomal vector (REVec) based on Borna disease virus 1 (BoDV-1) is a promising viral vector that achieves stable and long-term gene expression in transduced cells. However, the onerous procedure of reverse genetics used to generate an REVec is one of the challenges that must be overcome to make REVec technologies practical for use. In this study, to resolve the problems posed by reverse genetics, we focused on BoDV-2, a conspecific virus of BoDV-1 in the

Indexed as

Amino Acid SequenceAnimalsBorna DiseaseBorna disease virusCell NucleusChlorocebus aethiopsGenetic VectorsHEK293 CellsHumansNucleoproteinsPlasmidsReverse GeneticsRNA-Dependent RNA PolymeraseRNA, ViralVero CellsViral ProteinsNucleoproteinsRNA-Dependent RNA PolymeraseRNA, ViralViral ProteinsBorna disease virusnucleoproteinorthobornavirusvirus vector

Identifiers

PMID34406860
PMCPMC8513480
OpenAlexW3194227734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.