Evidence map›Paper›PMID 34406855›Full record

ArticlemSphere2021

Exposure to Parasitic Protists and Helminths Changes the Intestinal Community Structure of Bacterial Communities in a Cohort of Mother-Child Binomials from a Semirural Setting in Mexico.

Oswaldo Partida-Rodriguez, Miriam Nieves-Ramirez, Isabelle Laforest-Lapointe, Eric M Brown, Laura Parfrey, Alicia Valadez-Salazar, Lisa Thorson, Patricia Morán, Enrique Gonzalez, Edgar Rascon and 7 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  10. Detangling the Crosstalk BetweenFrontiers in cellular and infection microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Oswaldo Partida-RodriguezLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Miriam Nieves-RamirezLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Isabelle Laforest-LapointeDepartment of Physiology and Pharmacology, University of Calgarygrid.22072.35, Calgary, Alberta, Canada.
Eric M BrownMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbiagrid.17091.3e, Vancouver, British Columbia, Canada.
Laura ParfreyDepartment of Zoology, University of British Columbiagrid.17091.3e, Vancouver, British Columbia, Canada.
Alicia Valadez-SalazarLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Lisa ThorsonMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbiagrid.17091.3e, Vancouver, British Columbia, Canada.
Patricia MoránLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Enrique GonzalezLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Edgar RasconLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Ulises MagañaLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Eric HernandezLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Liliana Rojas-VelázquezLaboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
Javier TorresUnidad de Investigación en Enfermedades Infecciosas, UMAE Pediatria, IMSS, Mexico City, Mexico.
Marie Claire Arrieta *Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbiagrid.17091.3e, Vancouver, British Columbia, Canada.
Cecilia Ximenez *Laboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico.
B Brett Finlay *Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbiagrid.17091.3e, Vancouver, British Columbia, Canada.
Universidad Nacional Autónoma de México · MXUniversity of British Columbia · CAMexican Social Security Institute · MXUniversité de Sherbrooke · CA

Funding

CIHR
6 · The paper itself

Abstract

An estimated 3.5 billion people are colonized by intestinal parasites worldwide. Intestinal parasitic eukaryotes interact not only with the host but also with the intestinal microbiota. In this work, we studied the relationship between the presence of multiple enteric parasites and the community structures of gut bacteria and eukaryotes in an asymptomatic mother-child cohort from a semirural community in Mexico. Fecal samples were collected from 46 mothers and their respective children, with ages ranging from 2 to 20 months. Mothers and infants were found to be multiparasitized by Blastocystis hominis, Entamoeba dispar, Endolimax nana, Chilomastix mesnili, Iodamoeba butshlii, Entamoeba coli, Hymenolepis nana, and Ascaris lumbricoides. Sequencing of bacterial 16S rRNA and eukaryotic 18S rRNA genes showed a significant effect of parasite exposure on bacterial beta-diversity, which explained between 5.2% and 15.0% of the variation of the bacterial community structure in the cohort. Additionally, exposure to parasites was associated with significant changes in the relative abundances of multiple bacterial taxa, characterized by an increase in

Indexed as

AdolescentAdultAnimalsBacteriaCohort StudiesFecesFemaleGastrointestinal MicrobiomeHelminthsHost-Parasite InteractionsHumansInfantIntestinal Diseases, ParasiticMexicoMiddle AgedModels, StatisticalRNA, Ribosomal, 16S16S sequencing18S sequencingbacteriachildreneukaryoteshelminthsMexicomicrobiotaparasitesprotists

Identifiers

PMID34406855
PMCPMC8386383
OpenAlexW3196275782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.