Evidence map›Paper›PMID 34406827›Full record

ArticleApplied and environmental microbiology2021

Amyloid Aggregation of Streptococcus mutans Cnm Influences Its Collagen-Binding Activity.

Nicholas M di Cologna, Sandip Samaddar, Carolina A Valle, Jonathan Vargas, Alejandro Aviles-Reyes, Joyce Morales, Tridib Ganguly, Roberta Pileggi, L Jeannine Brady, José A Lemos and 1 more

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. The microbiota-proteostasis axis: implications in neurodegenerative diseases.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  2. Raman signatures ofFrontiers in microbiology · 2026
    Article
  3. Raman signatures ofFrontiers in microbiology · 2026
    Article
  4. Raman signatures ofFrontiers in microbiology · 2026
    Article
  5. Article
  6. Review
  7. Binding of IgA1 and surface-expressed collagen-binding protein ofFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Article
  10. Amyloid Fibrils Produced byInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Nicholas M di ColognaDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Sandip SamaddarDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Carolina A ValleDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Jonathan VargasDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Alejandro Aviles-ReyesDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Joyce MoralesDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Tridib GangulyDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
Roberta PileggiDepartment of Endodontics, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.
L Jeannine BradyDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0001-8952-086X
José A LemosDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0003-0791-5863
Jacqueline AbranchesDepartment of Oral Biology, University of Floridagrid.15276.37, College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-6615-7348
University of Florida · US

Funding

Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
Intracellular Invasion by Streptococcus mutans: Significance in DiseaseR01DE022559 · NIDCR · UNIVERSITY OF ROCHESTER · PI Jacqueline Abranches, Christine M. Szymanski · 2013 to 2026
$4.8M
Functional Amyloid Formation in Streptococcus mutansR01DE021789 · NIDCR · UNIVERSITY OF FLORIDA · PI BRADY, L. JEANNINE, LONG, JOANNA R · 2012 to 2021
$3.7M
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE021789HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE022559NIDCR NIH HHS R01 DE021789NIDCR NIH HHS R01 DE022559NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

The

Indexed as

AmyloidStreptococcus mutansAdhesins, BacterialAmyloidogenic ProteinsCarrier ProteinsCollagenAdhesins, BacterialAmyloidAmyloidogenic ProteinsCarrier ProteinsCnm protein, Streptococcus mutansCollagenbiofilmsCnmcollagen-binding proteinfunctional amyloidoral microbiologyStreptococcus mutanssurface proteins

Identifiers

PMID34406827
PMCPMC8516039
OpenAlexW3193464049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.