Evidence map›Paper›PMID 34406811›Full record

ArticleMicrobiology spectrum2021

Retrospective Diagnostic Accuracy Study of Abbott RealTi

Patrick Howlett, Pamela Nabeta, Nestan Tukvadze, Samuel G Schumacher, Claudia M Denkinger

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Diagnostic accuracy of Xpert MTB/RIF Ultra for detecting pulmonary tuberculosis and rifampicin resistance: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

Patrick HowlettNational Heart & Lung Institute, Imperial College Londongrid.7445.2, London, United Kingdom.ORCID 0000-0003-2381-7067
Pamela NabetaFoundation for Innovative New Diagnosticsgrid.452485.a, Geneva, Switzerland.
Nestan TukvadzeFoundation for Innovative New Diagnosticsgrid.452485.a, Geneva, Switzerland.
Samuel G Schumacher *Foundation for Innovative New Diagnosticsgrid.452485.a, Geneva, Switzerland.ORCID 0000-0002-6136-206X
Claudia M Denkinger *Foundation for Innovative New Diagnosticsgrid.452485.a, Geneva, Switzerland.ORCID 0000-0002-7216-7067
FIND · CHImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput centralized testing for tuberculosis (TB) and drug resistance is important, but comparative data are limited. In this retrospective cross-sectional study, participants were recruited from Johannesburg, South Africa, and Tbilisi, Georgia. The index tests, Abbott RealTi

Indexed as

AdultAntitubercular AgentsCross-Sectional StudiesDiagnostic Tests, RoutineDrug Resistance, BacterialFemaleHumansIsoniazidMaleMicrobial Sensitivity TestsMiddle AgedMolecular Diagnostic TechniquesMycobacterium tuberculosisRetrospective StudiesRifampinSouth AfricaAntitubercular AgentsIsoniazidRifampindiagnosticspulmonarypulmonary infectiontuberculosis

Identifiers

PMID34406811
PMCPMC8552641
OpenAlexW3194358151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.