Evidence map›Paper›PMID 34406608›Full record

Observational studyCanadian journal of anaesthesia = Journal canadien d'anesthesie2021

The association of nitrous oxide on length of stay in the postanesthesia care unit: a retrospective observational study.

Salameh Sameh Obeidat, Karuna Wongtangman, Michael Blank, Luca J Wachtendorf, Maximilian Hammer, Maximilian S Schaefer, Peter Santer, Matthias Eikermann, Eswar Sundar

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Nitrous oxide and length of stay in the postanesthesia care unit.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022
    Article
  3. In reply: Nitrous oxide can help reduce length of stay in the postanesthesia care unit.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Salameh Sameh Obeidat *Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Karuna Wongtangman *Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Michael Blank *Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Luca J WachtendorfDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Maximilian HammerDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Maximilian S SchaeferDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Peter SanterDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Matthias EikermannDepartment of Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA. meikermann@montefiore.org.ORCID http://orcid.org/0000-0002-7893-0596
Eswar SundarDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess whether intraoperative use of nitrous oxide (N

methodsWe analyzed data from adult patients who underwent non-cardiothoracic surgery under general anesthesia between May 2008 and December 2018. We assessed the association between intraoperative low- and high-dose N

resultsA total of 148,284 patients were included in the primary analysis. After adjusting for a priori defined confounders, a high dose of N

conclusionsNitrous oxide was dose-dependently associated with a decreased PACU length of stay. The effect was clinically relevant (> 30 min difference) in patients who underwent complex surgical procedures and received intraoperative antiemetic therapy.

Indexed as

AntiemeticsNitrous OxideAdultAnesthesia, GeneralHumansLength of StayRetrospective StudiesAntiemeticsNitrous Oxidegeneral anesthesiaintraoperative antiemeticsintraoperative nitrous oxideperioperative carepostanesthesia care unit length of stay

Identifiers

PMID34406608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.