Evidence map›Paper›PMID 34406577›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Belgian population norms for the EQ-5D-5L, 2018.

Lisa Van Wilder, Rana Charafeddine, Philippe Beutels, Robin Bruyndonckx, Irina Cleemput, Stefaan Demarest, Delphine De Smedt, Niel Hens, Aline Scohy, Niko Speybroeck and 5 more

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  4. Testing culturally relevant EQ-5D-5L bolt-ons for the Chinese general population: first quantitative phase of a mixed methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  9. Identifying and developing culturally relevant EQ-5D-5L bolt-on items for Chinese population: qualitative phase of a mixed-methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  11. Population norms for the EQ-5D-5L for Hungary: comparison of online surveys and computer assisted personal interviews.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
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  18. Health-related quality of life in psychiatric outpatients: a cross-sectional study of associations with symptoms, diagnoses, and employment status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lisa Van WilderDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0003-4394-2623
Rana CharafeddineDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Philippe BeutelsCentre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium.
Robin BruyndonckxInstitute for Biostatistics and Statistical Bioinformatics (I-BioStat), Data Science Institute, Hasselt University, Diepenbeek, Belgium.
Irina CleemputBelgian Health Care Knowledge Centre (KCE), Brussels, Belgium.ORCID http://orcid.org/0000-0003-4479-8950
Stefaan DemarestDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Delphine De SmedtDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.
Niel HensCentre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium.
Aline ScohyDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Niko SpeybroeckInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium.
Johan Van der HeydenDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Renata T C YokotaDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Herman Van OyenDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.
Joke BilckeCentre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium.ORCID http://orcid.org/0000-0001-5720-5291
Brecht DevleesschauwerDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium. brecht.devleesschauwer@sciensano.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHealth-related quality of life outcomes are increasingly used to monitor population health and health inequalities and to assess the (cost-) effectiveness of health interventions. The EQ-5D-5L has been included in the Belgian Health Interview Survey, providing a new source of population-based self-perceived health status information. This study aims to estimate Belgian population norms for the EQ-5D-5L by sex, age, and region and to analyze its association with educational attainment.

methodsThe BHIS 2018 provided EQ-5D-5L data for a nationally representative sample of the Belgian population. The dimension scores and index values were analyzed using logistic and linear regressions, respectively, accounting for the survey design.

resultsMore than half of respondents reported problems of pain/discomfort, while over a quarter reported problems of anxiety/depression. The average index value was 0.84. Women reported more problems on all dimensions, but particularly on anxiety/depression and pain/discomfort, resulting in significantly lower index values. Problems with mobility, self-care, and usual activities showed a sharp increase after the age of 80 years. Consequently, index values decreased significantly by age. Lower education was associated with a higher prevalence of problems for all dimensions except anxiety/depression and with a significantly lower index value.

conclusionThis paper presents the first nationally representative Belgian population norms using the EQ-5D-5L. Inclusion of the EQ-5D in future surveys will allow monitoring over time of self-reported health, disease burden, and health inequalities.

Indexed as

Health StatusQuality of LifeAged, 80 and overBelgiumFemaleHealth SurveysHumansSurveys and QuestionnairesEQ-5DHealth inequalitiesHealth interview surveyHealth-related quality of lifeHealth statusMulti-attribute utility instrumentPopulation normsVisual analogue scale

Identifiers

PMID34406577
PMCPMC8847192

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.