ArticleLasers in medical science2022
Plasmonic hyperthermia or radiofrequency electric field hyperthermia of cancerous cells through green-synthesized curcumin-coated gold nanoparticles.
Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Sub-15 nm Nanoparticles for Drug Delivery: Emerging Frontiers and Therapeutic Potential.International journal of molecular sciences · 2025Review
- Light-Responsive Nanoantennas Integrated into Nanoscale Metal-Organic Frameworks for Photothermal Drug Delivery.Small science · 2024Article
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- Advancing Gastrointestinal Health: Curcumin's Efficacy and Nanopreparations.Molecules (Basel, Switzerland) · 2024Review
- Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review.International journal of nanomedicine · 2024Review
- Current Overview of Metal Nanoparticles' Synthesis, Characterization, and Biomedical Applications, with a Focus on Silver and Gold Nanoparticles.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Investigation of effects of transferrin-conjugated gold nanoparticles on hippocampal neuronal activity and anxiety behavior in mice.Molecular and cellular biochemistry · 2023Article
- Radiosensitising effect of iron oxide-gold nanocomplex for electron beam therapy of melanoma in vivo by magnetic targeting.IET nanobiotechnology · 2023Article
- Inorganic Nanomaterials Used in Anti-Cancer Therapies:Further Developments.Nanomaterials (Basel, Switzerland) · 2023Review
- Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers.Molecules (Basel, Switzerland) · 2023Article
- Article
- The Therapeutic Effects of Curcumin-coated Gold Nanoparticle Against Leishmania Major Causative Agent of Zoonotic Cutaneous Leishmaniasis (ZCL): An In Vitro and In Vivo Study.Current microbiology · 2023Article
- How Synthesis of Algal Nanoparticles Affects Cancer Therapy? - A Complete Review of the Literature.International journal of nanomedicine · 2023Review
- Article
- Hydrophilic gold nanospheres: influence of alendronate, memantine, and tobramycin on morphostructural features.BMC chemistry · 2022Article
- Folate functionalized gold-coated magnetic nanoparticles effect in combined electroporation and radiation treatment of HPV-positive oropharyngeal cancer.Medical oncology (Northwood, London, England) · 2022Article
- Gold Nanoparticles: Biosynthesis and Potential of Biomedical Application.Journal of functional biomaterials · 2021Review
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanoparticle-mediated hyperthermia is one of the prominent adjuvant therapies which has been faced by many problematic challenges such as efficiency and safety. To compare the nanoparticle-mediated photothermal therapy and radiofrequency electric field hyperthermia, green-synthesized curcumin-coated gold nanoparticles (Cur@AuNPs) were applied in an in vitro study. Using recently published methodologies, each step of the study was performed. Through green chemistry, curcumin was applied as both a reducing and a capping agent in the gold nanoparticle synthesis process. Various techniques were applied for the characterization of the synthesized nanoparticles. The heating rate of Cur@AuNPs in the presence of RFEF or laser irradiation was recorded by using a non-contact thermometer. The cellular uptake of the Cur@AuNPs was studied by ICP-AES. The cellular viability and apoptosis rate of different treatment were measured to investigate the effect of two different nano-hyperthermia techniques on the murine colorectal cancer cell line. The average size of Cur@AuNPs was 7.2 ± 3.3 nm. The stability of the gold nanoparticles in the phosphate buffer saline with and without fetal bovine serum was verified by UV-Vis spectroscopy. FTIR, UV-Vis spectroscopy, and TEM indicate that the stability is a result of phenolic coating on the surface of nanoparticles. Cur@AuNPs can absorb both light and radiofrequency electric field exposure in a way that could kill cancerous cells in a significant number (30% in 64 μg/ml concentration). Green-synthesized Cur@AuNPs could induce apoptosis cell death in photothermal therapy and radiofrequency electric field hyperthermia.
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Registered trials
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