ArticleClinical research in cardiology : official journal of the German Cardiac Society2021
Global longitudinal strain predicts atrial fibrillation in individuals without hypertension: A Community-based cohort study.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Exploring the Feasibility of Integrating Cardiopulmonary Exercise Testing, Echocardiography, and Biomarkers for Predicting Atrial Fibrillation Recurrence: Rationale, Design and Protocol for a Prospective Cohort Study (The PLACEBO Trial).Journal of clinical medicine · 2025Article
- The incidence and risk factors of atrial high-rate episodes in patients with a dual-chamber pacemaker.Journal of arrhythmia · 2024Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundGlobal longitudinal strain (GLS) is a sensitive marker of myocardial dysfunction and atrial reservoir function. We sought to evaluate its value for predicting atrial fibrillation (AF) in the general population.
methodsParticipants from the Copenhagen City Heart Study examined with echocardiography, including speckle tracking analyses, were included. The endpoint was AF obtained through national registries. Proportional hazards Cox regression was applied, including multivariable adjustments made for CHADS
resultsThe data from 1,309 participants were analyzed. Of those, 153 (12%) developed AF during a median follow-up time of 15.9 years. The follow-up was 100%. The mean age was 57 years, 38% had hypertension, and GLS was - 18%. In unadjusted analysis, GLS was a univariable predictor of outcome (1.08 (1.04-1.13), p < 0.001, per 1% absolute decrease), but did not remain an independent predictor after adjusting for neither CHADS
conclusionGlobal longitudinal strain predicts AF in individuals without hypertension from the general population, independently of common risk scores.
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