ReviewInternational urogynecology journal2022
Colpocleisis as an obliterative surgery for pelvic organ prolapse: is it still a viable option in the twenty-first century? Narrative review.
Review in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06419075 (Local Infiltration of TranExamic Acid in Surgical Management of Pelvic Organ Prolapse), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Local Infiltration of TranExamic Acid in Surgical Management of Pelvic Organ Prolapse: a Pilot Randomized Clinical Trial
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fistulae Secondary to Vaginal Pessary Use for Pelvic Organ Prolapse: A Systematic Review.International urogynecology journal · 2025Pooled it
- Analysis of Clinical Characteristics of Partial Versus Total Colpocleisis for Pelvic Organ Prolapse: A Multicenter Retrospective Study in China.International urogynecology journal · 2026Article
- Urinary outcomes following colpocleisis without concomitant anti-incontinence procedure: A retrospective single-center study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Post-Hysterectomy Vaginal Vault Prolapse: Current Perspectives and Decision-Making Considerations for Surgical Treatment.Medicina (Kaunas, Lithuania) · 2026Review
- Comparison of Colpocleisis and Long-Term Pessary Therapy in the Management of Severe Pelvic Organ Prolapse: A Retrospective Observational Study.Gynecologic and obstetric investigation · 2026Article
- Article
- Predicting De Novo Stress Urinary Incontinence After Colpocleisis Using Clinical and Pelvic Floor Ultrasound Parameters: Development and Internal Validation of a Multimodal Model.International urogynecology journal · 2026Article
- Surgical treatment of apical prolapse Number 9 - 2026.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Review
- The comparison of colpocleisis and sacrospinous ligament fixation surgeries for treatment of vaginal vault prolapse: an observational study.Pakistan journal of medical sciences · 2025Article
- Post-colpocleisis pyocolpos: Three case reports.Case reports in women's health · 2025Article
- The Efficacy and Safety of Colpocleisis for Urinary Retention in Elderly Women With Pelvic Organ Prolapse.Cureus · 2025Article
- From Mesh to Modern Therapies: An Updated Narrative Review on Urogenital Prolapse.Journal of clinical medicine · 2025Review
- Pelvic Organ Prolapse: Current Challenges and Future Perspectives.Journal of clinical medicine · 2025Review
- Adaptations for Urogynecologic Surgery in Limited-Resource Settings: How to Do More with Less.International urogynecology journal · 2025Review
- Impact of Age on Perioperative Complications After Obliterative Vaginal Surgery.Urogynecology (Philadelphia, Pa.) · 2025Article
- Risk Factors and Prediction Model for Preoperative Lower-Extremity Venous Thrombosis in Elderly Women Undergoing Colpocleisis.International urogynecology journal · 2025Article
- Article
- Interpretable personalized surgical recommendation with joint consideration of multiple decisional dimensions.NPJ digital medicine · 2025Article
- Does Colpocleisis Still Hold Value? The Evolution of Apical Prolapse Surgery: A Comparative National Database Study.Journal of clinical medicine · 2025Article
- Development and Internal Validation of a Predictive Model for Deep Venous Thrombosis Following Colpocleisis in Elderly Patients with Pelvic Organ Prolapse.Risk management and healthcare policy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe aims were to review the literature from the last two decades and analyze treatment efficacy and findings of the studies on colpocleisis.
methodsA systematic search was conducted within the MEDLINE/PubMed and ClinicalTrials.gov databases, using the following keywords: pelvic organ prolapse (POP), colpocleisis, obliterative, and LeFort. All English full-text prospective and retrospective observational and interventional studies were included. Anatomical and subjective success, surgical techniques, concomitant procedures, complication rates, anesthesia methods, and decision regret were analyzed.
resultsA total of 237 papers were identified and 49 met the inclusion criteria. Mean patient age was 69.0 ± 8.0 to 84 ± 3.1. Over 90.2% of patients undergoing colpocleisis were diagnosed with POP stage ≥ 3. The follow-up ranged from 30 days to a median of 5 years. Anatomical success, defined as POP-Q stage ≤ 1 and no prolapse beyond the hymen, was achieved in 62.5 to 100% and 87.5 to 100% of all patients respectively. Subjective success ranged from 88% to 100%. Regret over the loss of coital ability ranged from 0% in many studies to 12.9%, general decision regret from 0% to 13.8%. After concomitant midurethral sling surgery, 86.8% to 94% of all patients were continent, with a 0-14% sling revision rate due to urinary retention. Urinary tract infection was the most common postoperative complication (4.3 to 9% confirmed with urine culture, 34.7% based on symptom definition). Bowel (0 to 2.7%) and urinary tract (0 to 9.1%) injuries were the consequences of concomitant procedures. The mortality rates were up to 1.3%.
conclusionsColpocleisis is a heterogeneous procedure, characterized by high subjective and objective success, low coital ability regret, and a low risk of complications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.