Evidence map›Paper›PMID 34406047›Full record

ArticleThe CRISPR journal2021

CRISPRclassify: Repeat-Based Classification of CRISPR Loci.

Matthew A Nethery, Michael Korvink, Kira S Makarova, Yuri I Wolf, Eugene V Koonin, Rodolphe Barrangou

Open access · greenAbstract read
In one paragraph

Article in The CRISPR journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Enhanced editing ofApplied and environmental microbiology · 2026
    Article
  5. Review
  6. Review
  7. Evolutionary trends inmSystems · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Matthew A NetheryGenomic Sciences Graduate Program, North Carolina State University, Raleigh, North Carolina, USA; National Library of Medicine, Bethesda, Maryland, USA.
Michael KorvinkITS Data Science, Premier Inc., Charlotte, North Carolina, USA; and National Library of Medicine, Bethesda, Maryland, USA.
Kira S MakarovaNational Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, USA.
Yuri I WolfNational Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, USA.
Eugene V KooninNational Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, USA.
Rodolphe BarrangouGenomic Sciences Graduate Program, North Carolina State University, Raleigh, North Carolina, USA; National Library of Medicine, Bethesda, Maryland, USA.
National Center for Biotechnology Information · USUnited States National Library of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection and classification of CRISPR-Cas systems in metagenomic data have become increasingly prevalent in recent years due to their potential for diverse applications in genome editing. Traditionally, CRISPR-Cas systems are classified through reference-based identification of proximate

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene EditingGenetic LociAlgorithmsArea Under CurveBase SequenceComputational BiologyDatabases, GeneticGenome, BacterialGenomicsReproducibility of Results

Identifiers

PMID34406047
PMCPMC8392126
OpenAlexW3195330678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.