Evidence map›Paper›PMID 34405988›Full record

ArticleACS applied materials & interfaces2021

Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption.

Konstantin Tamarov, Julie Tzu-Wen Wang, Juuso Kari, Emilia Happonen, Ilkka Vesavaara, Matti Niemelä, Paavo Perämäki, Khuloud T Al-Jamal, Wujun Xu, Vesa-Pekka Lehto

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Different conjugates of FeRSC advances · 2025
    Article
  5. Article
  6. Article
  7. Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Article
  8. Nonviral nanoparticle gene delivery into the CNS for neurological disorders and brain cancer applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Konstantin TamarovDepartment of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio 70211, Finland.ORCID https://orcid.org/0000-0003-0087-4878
Julie Tzu-Wen WangSchool of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London SE1 9NH, U.K.
Juuso KariDepartment of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio 70211, Finland.
Emilia HapponenDepartment of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio 70211, Finland.
Ilkka VesavaaraResearch Unit of Sustainable Chemistry, University of Oulu, Oulu 90570, Finland.
Matti NiemeläResearch Unit of Sustainable Chemistry, University of Oulu, Oulu 90570, Finland.
Paavo PerämäkiResearch Unit of Sustainable Chemistry, University of Oulu, Oulu 90570, Finland.
Khuloud T Al-JamalSchool of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London SE1 9NH, U.K.ORCID https://orcid.org/0000-0001-5165-2699
Wujun XuDepartment of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio 70211, Finland.ORCID https://orcid.org/0000-0002-3177-4709
Vesa-Pekka LehtoDepartment of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio 70211, Finland.ORCID https://orcid.org/0000-0001-8153-1070
University of Eastern Finland · FIUniversity of Oulu · FIKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Black porous silicon nanoparticles (BPSi NPs) are known as highly efficient infrared light absorbers that are well-suitable for photothermal therapy (PTT) and photoacoustic imaging (PAI). PTT and PAI require a sufficient number of effectively light-absorbing NPs to be accumulated in tumor after intravenous administration. Herein, biodistribution of PEGylated BPSi NPs with different sizes (i.e., 140, 200, and 300 nm in diameter) is investigated after intravenous administration in mice. BPSi NPs were conjugated with fluorescent dyes Cy5.5 and Cy7.5 to track them

Indexed as

AnimalsCarbocyaninesCell Line, TumorFemaleFluorescent DyesLiverMiceMice, Inbred BALB CNanoparticlesNeoplasmsOptical ImagingParticle SizePolyethylene GlycolsPorosityRAW 264.7 CellsSiliconCarbocyaninesCY5.5 cyanine dyeFluorescent DyesPolyethylene GlycolsSiliconbiodistributionblack porous siliconnanoparticlesPEGylationsize effectsurface modification

Identifiers

PMID34405988
PMCPMC8414481
OpenAlexW3193864255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.