Evidence map›Paper›PMID 34405591›Full record

ArticlePhysiological reports2021

Muscle-specific sirtuin 3 overexpression does not attenuate the pathological effects of high-fat/high-sucrose feeding but does enhance cardiac SERCA2a activity.

Christopher J Oldfield, Teri L Moffatt, Kimberley A O'Hara, Bo Xiang, Vernon W Dolinsky, Todd A Duhamel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Membrane Transporter of Serotonin and Hypercholesterolemia in Children.International journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christopher J OldfieldFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0003-2749-2335
Teri L MoffattFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB, Canada.
Kimberley A O'HaraInstitute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada.
Bo XiangDepartment of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Vernon W DolinskyDepartment of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Todd A DuhamelFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB, Canada.
St. Boniface Hospital · CAChildren's Hospital Research Institute of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, type 2 diabetes, and heart disease are linked to an unhealthy diet. Sarco(endo)plasmic reticulum calcium (Ca

Indexed as

AcetylationAnimalsCalcium SignalingDiabetic CardiomyopathiesDiet, Carbohydrate LoadingDiet, High-FatMaleMiceMice, Inbred C57BLMyocytes, CardiacSarcoplasmic Reticulum Calcium-Transporting ATPasesSirtuin 3Atp2a2 protein, mouseSarcoplasmic Reticulum Calcium-Transporting ATPasesSirt3 protein, mouseSirtuin 3acetylationcalcium handlingdiabetesobesitySERCAsirtuins

Identifiers

PMID34405591
PMCPMC8371348
OpenAlexW3194469015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.