Evidence map›Paper›PMID 34405588›Full record

Observational studyNursing open2021

Impact of adverse events on patient outcomes in a Japanese intensive care unit: a retrospective observational study.

Gen Aikawa, Akira Ouchi, Hideaki Sakuramoto, Chiemi Ono, Chie Hatozaki, Mayu Okamoto, Tetsuya Hoshino, Nobutake Shimojo, Yoshiaki Inoue

Abstract readObservational Study
In one paragraph

Observational study in Nursing open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gen AikawaDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-7404-5442
Akira OuchiDepartment of Adult Health Nursing, College of Nursing, Ibaraki Christian University, Hitachi, Japan.ORCID 0000-0003-4740-0098
Hideaki SakuramotoDepartment of Adult Health Nursing, College of Nursing, Ibaraki Christian University, Hitachi, Japan.ORCID 0000-0002-2370-2588
Chiemi OnoIntensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
Chie HatozakiIntensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
Mayu OkamotoIntensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
Tetsuya HoshinoDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nobutake ShimojoDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yoshiaki InoueDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe investigated adverse events (AEs) in a Japanese intensive care unit (ICU) and evaluated the impact of cause-specific AEs on mortality and length of stay.

designA retrospective observational study in the ICU of an academic hospital.

methodsWe reviewed medical records with the Global Trigger Tool.

resultsOf the 246 patients, 126 (51%) experienced one or more AEs with an incidence of 201 per 1000 patient-days and 115 per 100 admissions. A total of 294 AEs were detected with 119 (42%) adverse drug events, 67 (24%) procedural complications, 63 (22%) surgical complications, 26 (9%) nosocomial infections, 5 (2%) therapeutic errors and 4 (1%) diagnostic errors. Adverse event (AE) presence was associated with length of ICU stay (β = 2.85, 95% confidence interval [CI]: 1.09-4.61). Adverse drug events, procedural complications and nosocomial infections were strongly associated with length of ICU stay (β = 2.38, 95% CI: 0.77-3.98; β = 3.75, 95% CI: 2.03-5.48; β = 6.52, 95% CI: 4.07-8.97 respectively).

Indexed as

Intensive Care UnitsMedical ErrorsHospitalizationHumansJapanRetrospective Studiesadverse eventglobal trigger toolintensive carepatient safety

Identifiers

PMID34405588
PMCPMC8510737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.