Evidence map›Paper›PMID 34405579›Full record

ArticlePhysiological reports2021

The neuronal potassium current I

Michael Biet, Marc-André Dansereau, Philippe Sarret, Robert Dumaine

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The neuronal potassium current IPhysiological reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael BietDépartement de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Marc-André DansereauDépartement de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Philippe SarretDépartement de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Robert DumaineDépartement de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.ORCID 0000-0001-5874-1248
Université de Sherbrooke · CA

Funding

CIHR FDN-148413
6 · The paper itself

Abstract

Voltage-gated ion channels play a key role in the action potential (AP) initiation and its propagation in sensory neurons. Modulation of their activity during chronic inflammation creates a persistent pain state. In this study, we sought to determine how peripheral inflammation caused by complete Freund's adjuvant (CFA) alters the fast sodium (I

Indexed as

Action PotentialsAnimalsCalcium Channels, L-TypeCells, CulturedGanglia, SpinalMaleNeurons, AfferentNociceptionNociceptive PainPotassium Channels, Voltage-GatedRatsRats, Sprague-DawleySodium Channel BlockersSodium ChannelsTetrodotoxinCalcium Channels, L-TypePotassium Channels, Voltage-GatedSodium Channel BlockersSodium ChannelsTetrodotoxinchronic inflammationdorsal root gangliaelectrohysiologypain

Identifiers

PMID34405579
PMCPMC8371350
OpenAlexW3195439929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.