Evidence map›Paper›PMID 34405362›Full record

Trial reportDigestive diseases and sciences2022

Assessing the Efficacy and Outcomes Following Irrigation with Streptokinase Versus Hydrogen Peroxide in Necrotizing Pancreatitis: A Randomized Pilot Study.

M Venu Bhargava, Surinder Singh Rana, Ujjwal Gorsi, Mandeep Kang, Rajesh Gupta

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Review
  5. Article
  6. Percutaneous Biopsy and Drainage of the Pancreas.Seminars in interventional radiology · 2024
    Review
  7. Article
  8. Infected pancreatic necrosis-Current trends in management.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  9. Observational
  10. Time to think prime times for treatment of necrotizing pancreatitis: Pendulum conundrum.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2023
    Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M Venu Bhargava
Surinder Singh RanaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Ujjwal GorsiDepartment of Radio Diagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Mandeep KangDepartment of Radio Diagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Rajesh GuptaDepartment of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. rajsarakshi@gmail.com.ORCID 0000-0002-6585-1725
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous catheter drainage (PCD's) are prone to blockage because of necrosum. To improve the efficacy of PCD, necrolytic agents have been used. The present study compared the use of Streptokinase with H MATERIALS AND

methodsThis is a single-center randomized pilot study (from July 2018 to Dec 2019). Patients with infected pancreatic necrosis not showing response to PCD and saline irrigation were included in the study. Patients received either Streptokinase (Streptokinase group 50,000 IU in 100 ml normal saline) or 3% H

resultsThere were 30 patients in the study, 15 in each arm. Organ failure was seen in 23 (76.6%), single organ failure was present in 11 (47%), and multi-organ failure in 12 (53%). Bleeding complications (20% in H

Indexed as

DrainageHydrogen PeroxidePancreatitis, Acute NecrotizingHumansPilot ProjectsRetrospective StudiesSaline SolutionStreptokinaseTreatment OutcomeHydrogen PeroxideSaline SolutionStreptokinaseIrrigation of cavity with hydrogen peroxideIrrigation with streptokinaseNecrotizing pancreatitisPCD failure

Identifiers

PMID34405362
OpenAlexW3194955482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.