Evidence map›Paper›PMID 34405224›Full record

ArticleAge and ageing2021

Depressive symptom heterogeneity among older adults after hip fracture.

Jennifer M Kirk, Jay Magaziner, Michelle D Shardell, Alice S Ryan, Ann L Gruber-Baldini, Denise Orwig, Marc C Hochberg, Alan M Rathbun

Abstract read
In one paragraph

Article in Age and ageing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer M KirkDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-9656-5871
Jay MagazinerDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Michelle D ShardellDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Alice S RyanDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Ann L Gruber-BaldiniDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Denise OrwigDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Marc C HochbergDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Alan M RathbunDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
Statistical methods for vitamin D targets for functional outcomes in older adultsR01AG048069 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHARDELL, MICHELLE DENISE · 2015 to 2025
$4.3M
The Epidemiology of Bone Strength and Muscle Composition After Hip Fracture in MeR01AG029315 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2007 to 2011
$4.1M
A Feasibility and Pilot Study of Combined Treatment Protocol using Aerobic Exercise and Duloxetine in Older Adults with Symptomatic Knee Osteoarthritis and Comorbid DepressionK01AG064041 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RATHBUN, ALAN MICHAEL · 2019 to 2023
$619k
Epidemiology of the Inverse Comorbidity of Dementia and Cancer: Statistical Methods and Biological MechanismsR03AG070178 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHARDELL, MICHELLE DENISE · 2021 to 2021
$309k
NIA NIH HHS K01 AG064041NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG029315NIA NIH HHS R01 AG048069NIA NIH HHS R03 AG070178NIA NIH HHS R37 AG009901NIA NIH HHS T32 AG000262NIGMS NIH HHS R25 GM055036RRD VA IK6 RX003977
6 · The paper itself

Abstract

objectiveto evaluate patterns of depressive symptoms after hip fracture and examine their impact on functional recovery.

methodsparticipants (n = 304) included older adults from the Baltimore Hip Studies 7th cohort who experienced a hip fracture. Depressive symptoms were measured at baseline or 2-, 6- or 12-month post-hip fracture using the 20-item Center for Epidemiologic Studies Depression scale. Gait speed was measured after hip fracture at 2-, 6- or 12-month follow-up. Latent class analysis was used to identify individuals with similar patterns of depressive symptoms after hip fracture. Item response probabilities characterised symptom profiles, and posterior probability estimates were used to assign participants to a baseline depressive symptom subtype. Weighted estimated equations compared post-fracture gait speed between baseline symptomatic and asymptomatic groups.

resultsfour patterns of depressive symptoms were identified: asymptomatic (50.8%), somatic (28.6%), melancholic (11.4%) and anhedonic (9.2%). The somatic subtype was characterised by difficultly concentrating and reduced energy and movement, whereas anhedonic symptoms were associated with the inability to experience pleasure. Melancholic symptoms corresponded to anhedonia, decreased physical activity and other psychological and somatic complaints. Compared with the asymptomatic group, somatic symptoms were consistently associated with slower gait speed, -0.03 metres per second (m/s) and between-group differences for melancholic symptomology were as large as -0.05 m/s, but the associations were not statistically significant.

conclusionfindings demonstrate unique depressive symptom subtypes in older adults after hip fracture and provide confirmatory evidence of unique clinical phenotypes; however, their impact on functional recovery after hip fracture remains unclear.

Indexed as

DepressionHip FracturesAgedExerciseHumansRecovery of FunctionWalking Speeddepressionheterogeneityhip fractureolder peoplephysical performance

Identifiers

PMID34405224
PMCPMC8768453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.