ArticleAdvanced materials interfaces2019
Self-Regenerating Antimicrobial Polymer Surfaces via Multilayer-Design - Sequential and Triggered Layer Shedding under Physiological Conditions.
Article in Advanced materials interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 15 citations in OpenAlex.
- Death at the interface: Nanotechnology's challenging frontier against microbial surface colonization.Frontiers in chemistry · 2022Review
- Degradable Polymer Films Made from Poly(salicylic-acid-Macromolecular chemistry and physics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Regeneration of materials properties through surface regeneration could extend the lifetime of devices and is still an emerging field of research. (Self-)regenerating antimicrobial polymer surfaces could help to fight biofilm formation and related bacterial infections. In this paper, four different polymer multilayer designs for the regeneration of antimicrobial surfaces by layer shedding are presented. The multilayer architectures consist of 100-200 nm thick, discrete polymer layers. They are made from poly(guanidinium oxanorbornene) networks as the antimicrobial component, and different interlayers made from degradable poly(adipic anhydrides), depolymerizable poly(ethyl glyoxylate), or water-soluble poly(acrylamide). Layer shedding is designed to occur after hydrolysis, dissolution or depolymerization under simulated physiological conditions. The multilayer fabrication and disassembly is monitored by fluorescence microscopy, ellipsometry FT-IR spectroscopy and atomic force microscopy. By testing the antimicrobial activity of the restored surfaces, their functional integrity after layer shedding is confirmed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.