Evidence map›Paper›PMID 34405060›Full record

ArticleCureus2021

Scurvy: A Neglected Cause of Muscle Pain and Weakness in a Child With Picky Eating Behavior.

Ren Yi Kow, Nik Alyani Nik Abdul Adel, Ardilla Hanim Abdul Razak, Chooi Leng Low, Mohd Shukrimi Awang

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ren Yi KowDepartment of Orthopaedics, Traumatology & Rehabilitation, International Islamic University Malaysia, Kuantan, MYS.
Nik Alyani Nik Abdul AdelDepartment of Orthopaedics, Traumatology & Rehabilitation, International Islamic University Malaysia, Kuantan, MYS.
Ardilla Hanim Abdul RazakDepartment of Orthopaedics, Traumatology & Rehabilitation, International Islamic University Malaysia, Kuantan, MYS.
Chooi Leng LowDepartment of Radiology, International Islamic University Malaysia, Kuantan, MYS.
Mohd Shukrimi AwangDepartment of Orthopaedics, Traumatology & Rehabilitation, International Islamic University Malaysia, Kuantan, MYS.
International Islamic University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ascorbic acid (vitamin C) is an essential micronutrient that the human's body cannot synthesize endogenously. Scurvy, a disease of ascorbic acid deficiency, can manifest in a myriad of presentations. Due to its rarity in the modern world, scurvy is considered as a disease of the past. We present a paediatric case of scurvy with musculoskeletal manifestations as a result of picky eating behavior.  We report a previously healthy nine-year-old boy who presented with unexplained progressive bilateral lower limb generalized weakness and pain for two months. All initial biochemical and radiological investigations were unremarkable. Upon further history taking, he had severe picky eating behavior which raised the suspicion of scurvy. The diagnosis was confirmed with a serum ascorbic acid test. After ascorbic acid supplementation, his symptoms resolved immediately. Further food behavioral modification counselling to his family members helped to change his diet in a lasting way. As a result, he had no recurrence of symptoms. This case highlights the importance of having a high index of suspicion for an uncommon disease and emphasizes the need for a detailed dietary history upon patient's presentation.

Indexed as

ascorbic acideating behaviormuscle painpaediatric orthopedicsscurvyvitamin cweakness

Identifiers

PMID34405060
PMCPMC8352794
OpenAlexW3182881130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.