Evidence map›Paper›PMID 34404999›Full record

ReviewNano today2021

Antiviral nanoparticles for sanitizing surfaces: A roadmap to self-sterilizing against COVID-19.

Neil Lin, Daksh Verma, Nikhil Saini, Ramis Arbi, Muhammad Munir, Marko Jovic, Ayse Turak

Abstract readReview
In one paragraph

Review in Nano today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. SnOACS applied bio materials · 2025
    Article
  9. Article
  10. Engineering copper and copper-based materials for a post-antibiotic era.Frontiers in bioengineering and biotechnology · 2025
    Review
  11. Article
  12. Insight into the role of copper-based materials against the coronaviruses MHV-3, a model for SARS-CoV-2, during the COVID-19 pandemic.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Impact of Nanoparticle-Based TiOFoods (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Advanced Nanostructured Coatings Based on Doped TiOMolecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neil LinDepartment of Engineering Physics, McMaster University, Hamilton, Canada.
Daksh VermaDepartment of Engineering Physics, McMaster University, Hamilton, Canada.
Nikhil SainiDepartment of Engineering Physics, McMaster University, Hamilton, Canada.
Ramis ArbiDepartment of Engineering Physics, McMaster University, Hamilton, Canada.
Muhammad MunirDepartment of Engineering Physics, McMaster University, Hamilton, Canada.
Marko JovicNicoya Lifesciences, Kitchener, Canada.
Ayse TurakDepartment of Engineering Physics, McMaster University, Hamilton, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles provide new opportunities in merging therapeutics and new materials, with current research efforts just beginning to scratch the surface of their diverse benefits and potential applications. One such application, the use of inorganic nanoparticles in antiseptic coatings to prevent pathogen transmission and infection, has seen promising developments. Notably, the high reactive surface area to volume ratio and unique chemical properties of metal-based nanoparticles enables their potent inactivation of viruses. Nanoparticles exert their virucidal action through mechanisms including inhibition of virus-cell receptor binding, reactive oxygen species oxidation and destructive displacement bonding with key viral structures. The prevention of viral outbreaks is one of the foremost challenges to medical science today, emphasizing the importance of research efforts to develop nanoparticles for preventative antiviral applications. In this review, the use of nanoparticles to inactivate other viruses, such as influenza, HIV-1, or norovirus, among others, will be discussed to extrapolate broad-spectrum antiviral mechanisms that could also inhibit SARS-CoV-2 pathogenesis. This review analyzes the published literature to highlight the current state of knowledge regarding the efficacy of metal-based nanoparticles and other antiviral materials for biomedical, sterile polymer, and surface coating applications.

Indexed as

00-0199-00NanoparticlesSurface modificationsVirus inhibition

Identifiers

PMID34404999
PMCPMC8361009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.