ArticleMacromolecular chemistry and physics2018
A Degradable and Antimicrobial Surface-attached Polymer Hydrogel
Article in Macromolecular chemistry and physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Self-Regenerating Antimicrobial Polymer Surfaces via Multilayer-Design - Sequential and Triggered Layer Shedding under Physiological Conditions.Advanced materials interfaces · 2019Article
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Authors and funding
2 authors.
Funding
Abstract
Surface-attached, degradable polymer hydrogels with potential antimicrobial activity are reported. They were obtained by ring-opening metathesis copolymerization (ROMP) of a monomer with potential bioactivity and a monomer that carries a benzophenone cross-linker and a hydrolyzable group. The hydrolyzable group was either an ester or an anhydride group. The copolymers thus obtained were spin-coated onto silicon wafers and UV-irradiated to induce C,H cross-linking of the benzophenone groups and obtain the target polymer networks. Immersion of these networks into aqueous media triggered network degradation. The degradation speed depended on the nature of the intended break points (ester or anhydride groups), the number of cross-links per polymer chain, and the surrounding medium. By releasing bioactive polymer fragments to the medium ("leaching") and by regenerating the hydrogel surface during the degradation process, the hydrogels potentially have two ways to prevent biofilm formation on their surface.
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Registered trials
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