ArticleEuropean journal of clinical nutrition2022
Nutritional indices at admission are associated with mortality rates of patients in the intensive care unit.
Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 26 citations in OpenAlex.
- Comparative study on the predictive value of PNI and GNRI for all-cause mortality rates of elderly patients in cardiac care unit and cardiovascular intensive care unit.European journal of clinical nutrition · 2026Observational
- Dynamic changes in mortality risk factors for acute leukemia patients in the ICU and Post-ICU periods.Annals of hematology · 2026Article
- GNRI-stratified enteral nutrition protocol for elderly mechanically ventilated ICU patients: development and preliminary application.Frontiers in nutrition · 2026Article
- Association between prognostic nutritional index and 90-day mortality in septic patients: a retrospective cohort study.BMC nutrition · 2025Article
- A higher prognostic nutritional index is inversely associated with the need for renal replacement therapy in elderly critically Ill surgical patients.BMC surgery · 2025Article
- Can Nutritional Screening Tools Predict the Prognosis of Critically Ill Patients with Sepsis?Medicina (Kaunas, Lithuania) · 2025Observational
- Article
- Prognostic Nutritional Index Could Serve as a Reliable Prognostic Marker in Intensive Care Population.Medical sciences (Basel, Switzerland) · 2025Article
- Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death.Scientific reports · 2025Observational
- Advancing Nutritional Care Through Bioelectrical Impedance Analysis in Critical Patients.Nutrients · 2025Review
- Prognostic Nutritional Index (PNI) and Systemic Immune-Inflammatory Index (SII) as markers of severity among patients having COVID-19 infection.Journal of family medicine and primary care · 2024Article
- Relation between nutritional status on clinical outcomes of critically ill patients: emphasizing nutritional screening tools in a prospective cohort investigation.BMC nutrition · 2024Article
- The Addition of the Geriatric Nutritional Risk Index to the Prognostic Scoring Systems Did Not Improve Mortality Prediction in Trauma Patients in the Intensive Care Unit.Emergency medicine international · 2023Article
- The prognostic effects of the geriatric nutritional risk index on elderly acute kidney injury patients in intensive care units.Frontiers in medicine · 2023Article
- Nutritional Risk Assessment Scores Effectively Predict Mortality in Critically Ill Patients with Severe COVID-19.Nutrients · 2022Article
- Prevalence and Prognostic Impact of Malnutrition in Critical Patients With Acute Myocardial Infarction: Results From Chinese CIN Cohort and American MIMIC-III Database.Frontiers in nutrition · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is a common occurrence in critically ill patients, and has been related to poor prognosis in various diseases. Here, we assess the prognostic value of malnutrition using nutritional indices in intensive care units (ICU) patients.
methodsWe retrieved information on 2060 patients from the Medical Information Mart for Intensive Care III, and randomized the patients into training and validation cohorts, at a ratio of 7:3. We estimated their nutritional indices using prognostic nutritional index (PNI), geriatric nutritional risk index (GNRI), and controlling nutritional status (CONUT) score. Both multivariate regression analysis and the Kaplan-Meier (KM) survival curve were used to examine the prognostic role of nutritional indices in ICU mortality. Then we evaluated the additional predictive significance of each nutritional index beyond the baseline model including conventional risk factors.
resultsMultivariate regression analysis revealed that PNI, GNRI, and CONUT were independent predictors of in-hospital and 1-year mortality (all P < 0.001). KM curves showed higher 1-year mortality rates in having nutritional risk patients (PNI ≤ 38 or GNRI ≤ 98 or CONUT ≥ 2). Moreover, subgroup analyses revealed a significant association between each nutritional index and 1-year mortality in patients with different comorbidities. We also observed a pronounced additional impact on the predictive value of 1-year mortality when PNI, GNRI, and CONUT were separately added to the baseline model. The additional role of each nutritional index was further verified in the validation cohort.
conclusionsOur results revealed that the nutritional indices at admission are significantly correlated with increased mortality rates in ICU adult patients.
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