Evidence map›Paper›PMID 34404924›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Critical examination of relationships between early growth and childhood overweight in extremely preterm infants.

Tanis R Fenton, Roseann Nasser, Dianne Creighton, Seham Elmrayed, Selphee Tang, Chelsia Gillis, Belal Alshaikh

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03064022 (Preterm Infant Multicentre Growth Study), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03064022 completednot on this map

Preterm Infant Multicentre Growth Study

TypeobservationalSponsorUniversity of CalgaryRan2009 to 2019Enrolled1,275ConditionsPreterm InfantArmsGrowth
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Preterm growth assessment: the latest findings on age correction.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  3. Article
  4. Expected and Desirable Preterm and Small Infant Growth Patterns.Advances in nutrition (Bethesda, Md.) · 2024
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tanis R FentonCommunity Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. TFenton@ucalgary.ca.ORCID http://orcid.org/0000-0001-9585-9149
Roseann NasserNutrition and Food Services, Saskatchewan Health Authority, Regina, SK, Canada.
Dianne CreightonPediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Seham ElmrayedCommunity Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.ORCID http://orcid.org/0000-0001-6034-6140
Selphee TangAlberta Children's Hospital Neonatal Follow-up Clinic, Alberta Health Services, Calgary, AB, Canada.
Chelsia GillisCommunity Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Belal AlshaikhCommunity Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
University of Calgary · CAAlberta Health Services · CASaskatchewan Health Authority · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify the prevalence and risk factors for childhood overweight and obesity (OWO) at 3-year corrected age in children born <1500 g <29 weeks gestation. STUDY

designA multicentre retrospective cohort study for preterm infants admitted to neonatal intensive care units between 2001 and 2014.

resultsData were available for 911 (89.4%) of the 1019 infants who met the inclusion criteria. Of them, 22 (2.4%) had OWO. There were no associations between OWO and being small for gestational age (RR = 1.3, 95% confidence interval (CI): 0.3-5.4) or weight <10th percentile at 36 weeks (RR = 1.1, 95% CI: 0.4-2.8). OWO was associated with low maternal education (RR = 7.4, 95% CI: 2.1-26), maternal diabetes (RR = 5.2, 95% CI: 1.9-15) and neonatal brain injury (RR = 4.9, 95% CI: 1.8-14). Adjusting for concurrent child weight at 3 years of age resulted in an overadjustment bias.

conclusionSmall size at birth or at 36 weeks gestation in extremely preterm infants is not associated with increased risk of early childhood overgrowth or obesity. CLINICAL

trial registrationNCT03064022.

Indexed as

Infant, Extremely PrematurePediatric ObesityChildChild, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornInfant, Small for Gestational AgeRetrospective Studies

Identifiers

PMID34404924
OpenAlexW3194343963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.