Evidence map›Paper›PMID 34404798›Full record

ArticleNature communications2021

Light-fueled transient supramolecular assemblies in water as fluorescence modulators.

Xu-Man Chen, Xiao-Fang Hou, Hari Krishna Bisoyi, Wei-Jie Feng, Qin Cao, Shuai Huang, Hong Yang, Dongzhong Chen, Quan Li

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Multistate photoswitches beyond on and off.Nature communications · 2026
    Review
  3. Article
  4. Photoswitchable Merocyanine-Amphiphiles with Programmable Self-Assembly Times.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  5. Article
  6. Chemically-fueled phase transition of a redox-responsive polymer.Science and technology of advanced materials · 2025
    Article
  7. Article
  8. Article
  9. Toward Practical Single-Molecule/Atom Switches.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  10. Artificial molecular machines: Design and observation.Smart molecules : open access · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xu-Man ChenInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China.ORCID 0000-0002-3077-5806
Xiao-Fang HouKey Lab of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.
Hari Krishna BisoyiAdvanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH, USA.ORCID 0000-0002-9775-6757
Wei-Jie FengInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China.
Qin CaoInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China.
Shuai HuangInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China.
Hong YangInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China. yangh@seu.edu.cn.ORCID 0000-0003-4647-1388
Dongzhong ChenKey Lab of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China. cdz@nju.edu.cn.ORCID 0000-0001-7303-4533
Quan LiInstitute of Advanced Materials, School of Chemistry and Chemical Engineering, and Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing, China. quanli3273@gmail.com.ORCID 0000-0002-9042-360X
Southeast University · CNKent State University · USNanjing Tech University · CNNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dissipative self-assembly, which requires a continuous supply of fuel to maintain the assembled states far from equilibrium, is the foundation of biological systems. Among a variety of fuels, light, the original fuel of natural dissipative self-assembly, is fundamentally important but remains a challenge to introduce into artificial dissipative self-assemblies. Here, we report an artificial dissipative self-assembly system that is constructed from light-induced amphiphiles. Such dissipative supramolecular assembly is easily performed using protonated sulfonato-merocyanine and chitosan based molecular and macromolecular components in water. Light irradiation induces the assembly of supramolecular nanoparticles, which spontaneously disassemble in the dark due to thermal back relaxation of the molecular switch. Owing to the presence of light-induced amphiphiles and the thermal dissociation mechanism, the lifetimes of these transient supramolecular nanoparticles are highly sensitive to temperature and light power and range from several minutes to hours. By incorporating various fluorophores into transient supramolecular nanoparticles, the processes of aggregation-induced emission and aggregation-caused quenching, along with periodic variations in fluorescent color over time, have been demonstrated. Transient supramolecular assemblies, which act as fluorescence modulators, can also function in human hepatocellular cancer cells.

Indexed as

FluorescenceFluorescent DyesHep G2 CellsHumansKineticsMacromolecular SubstancesNanoparticlesTemperatureWaterFluorescent DyesMacromolecular SubstancesWater

Identifiers

PMID34404798
PMCPMC8371092
OpenAlexW3195638873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.