Evidence map›Paper›PMID 34404755›Full record

ArticleAging2021

TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells.

Hyunju Kim, Nahyun Choi, Doo Yeong Kim, So Yoon Kim, Seung Yong Song, Jong-Hyuk Sung

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Recent Advances in Drug Development for Hair Loss.International journal of molecular sciences · 2025
    Review
  8. Anti-Hair Loss Effect of Veratric Acid on Dermal Papilla Cells.International journal of molecular sciences · 2025
    Article
  9. Review
  10. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hyunju KimEpi Biotech Co., Ltd., Yeonsu-gu, Incheon 21984, South Korea.
Nahyun ChoiEpi Biotech Co., Ltd., Yeonsu-gu, Incheon 21984, South Korea.
Doo Yeong KimCollege of Pharmacy, Institute of Pharmaceutical Sciences, Yonsei University, Yeonsu-gu, Incheon 21983, South Korea.
So Yoon KimEpi Biotech Co., Ltd., Yeonsu-gu, Incheon 21984, South Korea.
Seung Yong SongDepartment of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seodaemun-gu, Seoul 03722, South Korea.
Jong-Hyuk SungEpi Biotech Co., Ltd., Yeonsu-gu, Incheon 21984, South Korea.
Epi Biotech Co., Ltd. (South Korea)Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermal papilla cells (DPCs) tend to aggregate both

Indexed as

AgingCell ProliferationCells, CulturedCellular SenescenceCollagenCollagen Type XIIIDermisHair FollicleHumansSpheroids, CellularTransforming Growth Factor beta2COL13A1 protein, humanCOL15A1 protein, humanCollagenCollagen Type XIIITGFB2 protein, humanTransforming Growth Factor beta2aggregationanti-agingcollagenhuman dermal papilla cellsTGF-beta2

Identifiers

PMID34404755
PMCPMC8436940
OpenAlexW3194227345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.