Evidence map›Paper›PMID 34404720›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Electrochemical borylation of carboxylic acids.

Lisa M Barton, Longrui Chen, Donna G Blackmond, Phil S Baran

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 74 citations in OpenAlex.

  1. Borylcyclopropanes: Synthetic Strategies and Applications.Angewandte Chemie (International ed. in English) · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. General Alkene 1,2-Journal of the American Chemical Society · 2024
    Article
  7. Article
  8. Article
  9. Mechanisms for radical reactions initiating fromBeilstein journal of organic chemistry · 2024
    Article
  10. Article
  11. Article
  12. Recent Advances in C(spACS organic & inorganic Au · 2022
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisa M BartonDepartment of Chemistry, Scripps Research, La Jolla, CA 92037.
Longrui ChenDepartment of Chemistry, Scripps Research, La Jolla, CA 92037.
Donna G BlackmondDepartment of Chemistry, Scripps Research, La Jolla, CA 92037 blackmond@scripps.edu pbaran@scripps.edu.
Phil S BaranDepartment of Chemistry, Scripps Research, La Jolla, CA 92037 blackmond@scripps.edu pbaran@scripps.edu.ORCID 0000-0001-9193-9053
Scripps Institution of Oceanography · US

Funding

Scalable Synthesis and New Bond DisconnectionsR35GM118176 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI BARAN, PHIL S · 2016 to 2025
$11.5M
NIGMS NIH HHS R35 GM118176
6 · The paper itself

Abstract

A simple electrochemically mediated method for the conversion of alkyl carboxylic acids to their borylated congeners is presented. This protocol features an undivided cell setup with inexpensive carbon-based electrodes and exhibits a broad substrate scope and scalability in both flow and batch reactors. The use of this method in challenging contexts is exemplified with a modular formal synthesis of jawsamycin, a natural product harboring five cyclopropane rings.

Indexed as

ElectrodesBoronic AcidsCarboxylic AcidsElectrochemical TechniquesBoronic AcidsCarboxylic Acidselectrochemistryorganic synthesistotal synthesis

Identifiers

PMID34404720
PMCPMC8403965
OpenAlexW3138010918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.