Evidence map›Paper›PMID 34404717›Full record

ArticleBMJ open2021

Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysis.

Nauzer Forbes, Grigorios I Leontiadis, Marcus Vaska, B Joseph Elmunzer, Yuhong Yuan, Kirles Bishay, Zhao Wu Meng, Jordan Iannuzzi, Dylan E O'Sullivan, Brittany Mah and 10 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Nauzer ForbesDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada nauzer.forbes@ucalgary.ca.ORCID 0000-0002-6966-3908
Grigorios I LeontiadisDepartment of Medicine, Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada.
Marcus VaskaKnowledge Resource Service, Alberta Health Services, Calgary, Alberta, Canada.
B Joseph ElmunzerDivision of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA.
Yuhong YuanFarncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Kirles BishayDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Zhao Wu MengDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Jordan IannuzziDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Dylan E O'SullivanDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Brittany MahDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Arun C R PartridgeDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-4191-0970
Amanda M HendersonDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Aatif QureshiDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Rajesh N KeswaniDivision of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Sachin WaniDivision of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Ronald J BridgesDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Steven J HeitmanDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.
Robert J HilsdenDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-1545-1093
Yibing RuanDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-2417-7172
Darren R BrennerDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-3027-290X
University of Calgary · CAAlberta Health Services · CAPopulation Health Research Institute · CAMedical University of South Carolina · USNorthwestern University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8M
NIDDK NIH HHS P30 DK123704
6 · The paper itself

Abstract

introductionEndoscopic retrograde cholangiopancreatography (ERCP) is performed to diagnose and manage conditions of the biliary and pancreatic ducts. Though effective, it is associated with common adverse events (AEs). The purpose of this study is to systematically review ERCP AE rates and report up-to-date pooled estimates. METHODS AND ANALYSIS: A comprehensive electronic search will be conducted of relevant medical databases through 10 November 2020. A study team of eight data abstracters will independently determine study eligibility, assess quality and abstract data in parallel, with any two concordant entries constituting agreement and with discrepancies resolved by consensus. The primary outcome will be the pooled incidence of post-ERCP pancreatitis, with secondary outcomes including post-ERCP bleeding, cholangitis, perforation, cholecystitis, death and unplanned healthcare encounters. Secondary outcomes will also include rates of specific and overall AEs within clinically relevant subgroups determined a priori. DerSimonian and Laird random effects models will be used to perform meta-analyses of these outcomes. Sources of heterogeneity will be explored via meta-regression. Subgroup analyses based on median dates of data collection across studies will be performed to determine whether AE rates have changed over time. ETHICS AND DISSEMINATION: Ethics approval is not required for this study as it is a planned meta-analysis of previously published data. Participant consent is similarly not required. Dissemination is planned via presentation at relevant conferences in addition to publication in peer-reviewed journals.

Indexed as

CholangitisPancreatitisCholangiopancreatography, Endoscopic RetrogradeHumansMeta-Analysis as TopicSystematic Reviews as Topicendoscopyhepatobiliary diseasepancreatic disease

Identifiers

PMID34404717
PMCPMC8372880
OpenAlexW3195665997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.