ArticleBMJ open2021
Association of depressive symptoms with the progression of carotid intima-media thickness in a community-based cohort in Beijing, China.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Article
- Prognostic significance of bilateral carotid plaque asymmetry for major cardiovascular events in high-risk patients: a 3-year retrospective cohort study.The international journal of cardiovascular imaging · 2025Article
- A simple score, CKMiScience · 2025Article
- A hybrid algorithm-based ECG risk prediction model for cardiovascular disease.European heart journal. Digital health · 2025Article
- Association of mental health in childhood, adolescence and young adulthood with cardiovascular risk factors and carotid remodeling below age 30 - results from the KiGGS cohort study.European journal of epidemiology · 2025Article
- Association Between Changes in Central Blood Pressure and Peripheral Blood Pressure With New-Onset Hypertension in a Chinese Community-Based Population.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the relationship between depressive symptoms and progression of carotid intima-media thickness (cIMT) in a Beijing community-based population.
designProspective cohort study between 2014 and 2018.
settingDwellers without cardiovascular disease, hypertension or diabetes from a Beijing community.
participants3849 Chinese community-dwelling individuals who underwent baseline screening for depressive symptoms were invited to participate in the study in 2014 and follow-up visit in 2018. Among them, 2124 participants completed carotid ultrasound examination both at baseline and a follow-up visit. After further excluding patients with a history of stroke, myocardial infarction or lower extremity arterial stenosis and those with a diagnosis of hypertension or diabetes and ankle-brachial index ≤0.9 at baseline, 1011 eligible participants were finally included. PRIMARY OUTCOME MEASURE: The rate of mean cIMT change.
resultsOver a median follow-up period of 4.40 years, the overall rate of mean cIMT change was 2.23% (-5.64% to 9.51%). After adjustment for 13 covariates, there was an increase of 2.36% (β=2.36, 95% CI: 0.37 to 4.36, p=0.020) for the rates of mean cIMT change in the depressive group compared with the control group. Furthermore, this association was modified by drinking status (β=3.22, 95% CI: 1.25 to 5.19, P-interaction=0.006).
conclusionDepressive symptoms were independently associated with progression of mean cIMT in a community-based cohort in Beijing, China. Furthermore, this relationship was modified by drinking status.
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