Evidence map›Paper›PMID 34404712›Full record

ArticleBMJ open2021

Epidemiological factors associated with the absence of previous HIV testing among HIV-positive persons in Singapore, 2012-2017.

Li Wei Ang, Matthias Paul Han Sim Toh, Irving Charles Boudville, Chen Seong Wong, Sophia Archuleta, Vernon Lee, Angela Chow, Yee Sin Leo

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Li Wei AngNational Centre for Infectious Diseases, Singapore li_wei_ang@ncid.sg.ORCID 0000-0002-0036-255X
Matthias Paul Han Sim TohNational Centre for Infectious Diseases, Singapore.
Irving Charles BoudvilleNational Centre for Infectious Diseases, Singapore.
Chen Seong WongNational Centre for Infectious Diseases, Singapore.
Sophia ArchuletaNational Centre for Infectious Diseases, Singapore.
Vernon LeeNational University of Singapore, Singapore.
Angela ChowNational Centre for Infectious Diseases, Singapore.
Yee Sin LeoNational Centre for Infectious Diseases, Singapore.
National University of Singapore · SGNational Centre for Infectious Diseases · SGMinistry of Health · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the temporal trend and identify risk factors associated with the absence of previous HIV testing prior to their diagnosis among HIV-positive persons in Singapore. STUDY

designCross-sectional. SETTING AND

participantsWe analysed data of HIV-positive persons infected via sexual transmission, who were notified to the National HIV Registry in 2012-2017. OUTCOMES: Epidemiological factors associated with the absence of HIV testing prior to diagnosis were determined separately for two groups of HIV-positive persons: early and late stages of HIV infection at diagnosis.

results2188 HIV-positive persons with information on HIV testing history and CD4 cell count were included in the study. The median age at HIV diagnosis was 40 years (IQR 30-51). Nearly half (45.1%) had never been tested for HIV prior to their diagnosis. The most common reason cited for no previous HIV testing was 'not necessary to test' (73.7%). The proportion diagnosed at late-stage HIV infection was significantly higher among HIV-positive persons who had never been tested for HIV (63.9%) compared with those who had undergone previous HIV tests (29.0%). Common risk factors associated with no previous HIV testing in multivariable logistic regression analysis stratified by stage of HIV infection were: older age at HIV diagnosis, lower educational level, detection via medical care and HIV infection via heterosexual transmission. In the stratified analysis for persons diagnosed at early-stage of HIV infection, in addition to the four risk factors, women and those of Malay ethnicity were also less likely to have previous HIV testing prior to their diagnosis.

conclusionTargeted prevention efforts and strategies are needed to raise the level of awareness of HIV/AIDS and to encourage early and regular screening among the at-risk groups by making HIV testing more accessible.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsAgedCross-Sectional StudiesFemaleHIV TestingHumansSingaporeepidemiologyHIV & AIDSpublic health

Identifiers

PMID34404712
PMCPMC8372883
OpenAlexW3196243074

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.