Evidence map›Paper›PMID 34404473›Full record

Trial reportTrials2021

Chlorhexidine-alcohol versus povidone-iodine as preoperative skin antisepsis for prevention of surgical site infection in cesarean delivery-a pilot randomized control trial.

Athokpam Lenin Luwang, Pradip Kumar Saha, Minakshi Rohilla, Pooja Sikka, Lekha Saha, Vikas Gautam

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Athokpam Lenin LuwangDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India.ORCID https://orcid.org/0000-0003-1707-6987
Pradip Kumar SahaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India. pradiplekha@yahoo.co.in.ORCID http://orcid.org/0000-0002-3200-4124
Minakshi RohillaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India.ORCID https://orcid.org/0000-0003-4954-5004
Pooja SikkaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India.ORCID https://orcid.org/0000-0002-6205-0455
Lekha SahaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India.ORCID https://orcid.org/0000-0001-5925-7159
Vikas GautamDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin 160012, India.ORCID https://orcid.org/0000-0001-5565-048X
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the efficacy of chlorhexidine-alcohol and povidone-iodine as preoperative antiseptic skin preparation for prevention of surgical site infection (SSI) after cesarean delivery (CD). MATERIALS AND

methodsA total of 311 eligible women who underwent CS were recruited in the study after fulfilling all the eligibility and exclusion criteria. Patients were randomized into two groups (153 in chlorhexidine-alcohol group and 158 in povidone-iodine group) by a computer-generated randomization table. Patients were followed for a period of 30 days in postoperative period to monitor for SSI.

resultsThe rate of SSI in the chlorhexidine-alcohol group is 5.4% and that of the povidone-iodine group is 8.6%. E. coli, K. pneumoniae, and Acinetobacter baumannii were the most common organisms isolated. E. coli was found in 9.5% of the total SSI cases.

conclusionsThe study found that the patients who received chlorhexidine-alcohol as skin antiseptic had less chance of developing SSI than those who received povidone-iodine; however, it did not reach a statistical significance.

trial registrationClinical Trials Registry of India CTRI/2018/05/014294 . Registered on May 31, 2018.

Indexed as

Anti-Infective Agents, LocalPovidone-IodineAntisepsisChlorhexidineEscherichia coliFemaleHumansPilot ProjectsPregnancyPreoperative CareSurgical Wound InfectionAnti-Infective Agents, LocalChlorhexidinePovidone-IodineAntisepticBetadineCesarean sectionChlorhexidine–alcoholSurgical site infection

Identifiers

PMID34404473
PMCPMC8369632
OpenAlexW3195457275

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.