Evidence map›Paper›PMID 34404426›Full record

ArticleCost effectiveness and resource allocation : C/E2021

Cost-effectiveness of a care manager collaborative care programme for patients with depression in primary care: 12-month economic evaluation of a pragmatic randomised controlled trial.

Anna Holst, Frida Labori, Cecilia Björkelund, Dominique Hange, Irene Svenningsson, Eva-Lisa Petersson, Jeanette Westman, Christina Möller, Mikael Svensson

Registry-linked trialAbstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02378272 (RCT on Care Manager Organization for Management of Mild-moderate Depression in the Primary Care Setting, Sweden), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02378272 nacompletednot on this map

RCT on Care Manager Organization for Management of Mild-moderate Depression in the Primary Care Setting, Sweden

TypeinterventionalSponsorGöteborg UniversityRan2014 to 2018Enrolled376ConditionsDepressionArmscare manager for depression
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna HolstPrimary Health Care/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Allmänmedicin, Box 453, 405 30, Gothenburg, Sweden. doktor.holst@gmail.com.ORCID http://orcid.org/0000-0001-8437-1586
Frida LaboriHealth Economics and Policy/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Cecilia BjörkelundPrimary Health Care/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Allmänmedicin, Box 453, 405 30, Gothenburg, Sweden.
Dominique HangePrimary Health Care/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Allmänmedicin, Box 453, 405 30, Gothenburg, Sweden.
Irene SvenningssonPrimary Health Care/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Allmänmedicin, Box 453, 405 30, Gothenburg, Sweden.
Eva-Lisa PeterssonPrimary Health Care/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Allmänmedicin, Box 453, 405 30, Gothenburg, Sweden.
Jeanette WestmanDivision of Nursing, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Christina MöllerPrimary Health Care Head Office, Närhälsan, Region Västra Götaland, Gothenburg, Sweden.
Mikael SvenssonHealth Economics and Policy/School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Funding

Swedish Insitute ALF-GBG-722441
6 · The paper itself

Abstract

objectivesTo study the cost-effectiveness of a care manager organization for patients with mild to moderate depression in Swedish primary care in a 12-month perspective.

methodsCost-effectiveness analysis of the care manager organization compared to care as usual (CAU) in a pragmatic cluster randomised controlled trial including 192 individuals in the care manager group and 184 in the CAU group. Cost-effectiveness was assessed from a health care and societal perspectives. Costs were assessed in relation to two different health outcome measures: depression free days (DFDs) and quality adjusted life years (QALYs).

resultsAt the 12-month follow-up, patients treated at the intervention Primary Care Centres (PCCs) with a care manager organization had larger health benefits than the group receiving usual care only at control PCCs. Mean QALY per patient was 0.73 (95% CI 0.7; 0.75) in the care manager group compared to 0.70 (95% CI 0.66; 0.73) in the CAU group. Mean DFDs was 203 (95% CI 178; 229) in the care manager group and 155 (95% CI 131; 179) in the CAU group. Further, from a societal perspective, care manager care was associated with a lower cost than care as usual, resulting in a dominant incremental cost-effectiveness ratio (ICER) for both QALYs and DFDs. From a health care perspective care manager care was related to a low cost per QALY (36,500 SEK / €3,379) and DFD (31 SEK/€3). LIMITATIONS: A limitation is the fact that QALY data was impaired by insufficient EQ-5D data for some patients.

conclusionsA care manager organization at the PCC to increase quality of care for patients with mild-moderate depression shows high health benefits, with no decay over time, and high cost-effectiveness both from a health care and a societal perspective. Trial registration details: The trial was registered in ClinicalTrials.com ( https://clinicaltrials.gov/ct2/show/NCT02378272 ) in 02/02/2015 with the registration number NCT02378272. The first patient was enrolled in 11/20/2014.

Indexed as

Care managerCollaborative careCost-effectivenessDepressionPrimary careSweden

Identifiers

PMID34404426
PMCPMC8369323

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.