ArticleCirculation research2021
Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Immunological maladaptation preceding spontaneous preterm birth in human pregnancies.Nature communications · 2026Article
- Placental nicotinamide adenine dinucleotide modulates the timing of labor.Science (New York, N.Y.) · 2026Article
- Reelin regulates the migration and differentiation of extravillous trophoblastic cells.Biological research · 2026Article
- B Cell Tolerance and Obstetric Antiphospholipid Syndrome.Clinical reviews in allergy & immunology · 2025Review
- Maternal Immune Activation: Implications for Congenital Heart Defects.Clinical reviews in allergy & immunology · 2025Review
- Novel advances on pathophysiological mechanisms, clinical manifestations, and treatment of antiphospholipid syndrome.Frontiers in immunology · 2025Review
- Impact of antiphospholipid syndrome on placenta and uterine NK cell function: insights from a mouse model.Scientific reports · 2024Article
- Exosomal miR-146a-5p derived from human umbilical cord mesenchymal stem cells can alleviate antiphospholipid antibody-induced trophoblast injury and placental dysfunction by regulating the TRAF6/NF-κB axis.Journal of nanobiotechnology · 2023Article
- The pathogenesis of obstetric APS: a 2023 update.Clinical immunology (Orlando, Fla.) · 2023Review
- Trophoblast Cell Function in the Antiphospholipid Syndrome.Biomedicines · 2023Review
- Article
- Animal Models of Cardiovascular Complications of Pregnancy.Circulation research · 2022Review
- Differences in Endothelial Activation and Dysfunction Induced by Antiphospholipid Antibodies Among Groups of Patients With Thrombotic, Refractory, and Non-refractory Antiphospholipid Syndrome.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
20 authors at 8 institutions in 2 countries.
Haiyan ChuCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).ORCID 0000-0002-1901-1717
Anastasia SacharidouCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).
An NguyenCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).ORCID 0000-0001-6119-816X
Chun LiCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).
Ken L ChamblissCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).
Jane E SalmonMedicine, Hospital for Special Surgery, Weill Cornell Medical College, New York (J.E.S.).
Yu-Min ShenInternal Medicine (Y.-M.S., D.K.M.), University of Texas Southwestern Medical Center, Dallas.
Julie LoObstetrics and Gynecology (J.L.), University of Texas Southwestern Medical Center, Dallas.
Gustavo W LeoneFroedtert-Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee (G.W.L.).
Joachim HerzMolecular Genetics (J.H.), University of Texas Southwestern Medical Center, Dallas.ORCID 0000-0002-8506-3400
David Y HuiPathology, University of Cincinnati College of Medicine (D.Y.H.).ORCID 0000-0001-7333-2151
Denise K MarcianoInternal Medicine (Y.-M.S., D.K.M.), University of Texas Southwestern Medical Center, Dallas.
Vikki M AbrahamsObstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT (V.M.A.).
Bryony V NataleObstetrics, Gynecology & Reproductive Science, University of California San Diego, La Jolla (B.V.N., D.R.N.).
Alina P MontalbanoBiochemistry and Obstetrics and Gynecology (A.P.M.), University of Texas Southwestern Medical Center, Dallas.ORCID 0000-0002-9098-0617
Xue XiaoPopulation and Data Sciences and Pediatrics (X.X., L.X.), University of Texas Southwestern Medical Center, Dallas.
Lin XuPopulation and Data Sciences and Pediatrics (X.X., L.X.), University of Texas Southwestern Medical Center, Dallas.
David R NataleObstetrics, Gynecology & Reproductive Science, University of California San Diego, La Jolla (B.V.N., D.R.N.).ORCID 0000-0001-8365-455X
Philip W ShaulCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).ORCID 0000-0003-1157-4002
Chieko MineoCenter for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).ORCID 0000-0002-4978-6177
Center for Vascular Biology Research · USThe University of Texas Southwestern Medical Center · USQueen's University · CAFroedtert Hospital · USHospital for Special Surgery · USSouthwestern Medical Center · USUniversity of Cincinnati Medical Center · USYale University · US
Funding
TRAINING PROGRAM IN LUNG BIOLOGY AND DISEASET32HL098040 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAUL, PHILIP W, TERADA, LANCE S · 2009 to 2024
$4.6MValidation of Modulators of PGRN as Novel Therapeutics for Frontotemporal DementiR01NS108115 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI HAGGARTY, STEPHEN J, HERZ, JOACHIM J · 2018 to 2022
$4.0MMetabolism of the VLDL receptor and ApoE receptor 2R37HL063762 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2010 to 2019
$4.0MApoE receptor-2 in vascular disease progression and regressionR01HL147403 · NHLBI · UNIVERSITY OF CINCINNATI · PI HUI, DAVID YIU-KWAN · 2019 to 2022
$3.0MRole of Endothelial and Macrophage ApoER2 in Atherosclerosis ModulationR01HL118001 · NHLBI · UNIVERSITY OF CINCINNATI · PI HUI, DAVID YIU-KWAN, SHAUL, PHILIP W · 2014 to 2017
$2.8MUnraveling ApoE4 Promotion of Cardiometabolic DiseaseR01HL144969 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAUL, PHILIP W · 2020 to 2023
$2.6MPhysiology and Pathophysiology of Apolipoprotein E receptor-2 splicing in Alzheimer's diseaseRF1AG053391 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2016 to 2020
$2.4MMolecular Basis of Synaptic Suppression by ApoER01NS093382 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2016 to 2020
$2.0M(PQ1) Epigenetic effects of the premalignant fieldR01CA208620 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI TERADA, LANCE S · 2016 to 2020
$1.9MMolecular Basis of Pregnancy Complications in the Antiphospholipid SyndromeR01HD094395 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI MINEO, CHIEKO · 2018 to 2022
$1.8MEndothelial Basis of Obesity-induced Insulin ResistanceR01DK110127 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MINEO, CHIEKO · 2016 to 2019
$1.8MStress-mediated trophoblast proliferation: adaptation or pathology?R01HD100179 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LAURENT, LOUISE CHANG, NATALE, DAVID RENATO CHRISTOPHER · 2019 to 2023
$1.7MCIHR 201203MOP-275374-CIA-CBBA-109624NCI NIH HHS R01 CA208620NHLBI NIH HHS R01 HL109604NHLBI NIH HHS R01 HL118001NHLBI NIH HHS R01 HL144969NHLBI NIH HHS R01 HL147403NHLBI NIH HHS R37 HL063762NHLBI NIH HHS T32 HL098040NIA NIH HHS RF1 AG053391NICHD NIH HHS R01 HD094395NICHD NIH HHS R01 HD100179NIDDK NIH HHS R01 DK110127NINDS NIH HHS R01 NS093382NINDS NIH HHS R01 NS108115
Abstract
[Figure: see text].
Indexed as
Adaptor Proteins, Signal TransducingAnimalsAntibodies, AntiphospholipidAntiphospholipid SyndromeApoptosis Regulatory ProteinsCell LineFemaleHumansHypoxia-Inducible Factor 1, alpha SubunitLDL-Receptor Related ProteinsMiceMice, Inbred C57BLPre-EclampsiaPregnancyProtein Phosphatase 2TrophoblastsAdaptor Proteins, Signal TransducingAntibodies, AntiphospholipidApoptosis Regulatory ProteinsDab2 protein, mouseHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitLDL-Receptor Related Proteinslow density lipoprotein receptor-related protein 8Protein Phosphatase 2Spag9 protein, mouseantiphospholipid syndromeendoglinplacentapreeclampsiaproteinuriatrophoblasts
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.