Evidence map›Paper›PMID 34404162›Full record

ArticleZhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns2021

[Clinical application and mechanism of botulinum toxin type A in scar treatment].

Y X Zhang, S N Zhang

Open access · greenAbstract read
In one paragraph

Article in Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 0 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Y X ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
S N ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Shanghai Ninth People's Hospital · CN

Funding

Clinical Research Booster Program of Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine JYLJ027Clinical Research Booster Program of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine JYLJ027Construction Project of Clinical Research Multidisciplinary Diagnosis and Treatment Team of Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 2017-1-007Construction Project of Clinical Research Multi-Disciplinary Diagnosis and Treatment Team of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 2017-1-007Excellent Technology Leader Plan of Shanghai Science and Technology Commission 18XD1423700Excellent Technology Leader Plan of Shanghai Science and Technology Commission of China 18XD1423700General Program of National Natural Science Foundation of China 81772098Peak Plateau Plan of Shanghai Education Commission "Research Doctors" Project 20152227Peak Plateau Plan of Shanghai Education Commission "Research Doctors" Project of China 20152227Youth Program of National Natural Science Foundation of China 81801917, 81801918
6 · The paper itself

Abstract

Pathological scars cause both local physical discomforts and mental disorders for patients. With the development of research, botulinum toxin type A (BTX-A) has been gradually used in the clinical treatment of scars. This article summarizes three potential mechanisms of BTX-A, including early tension reduction, inhibition of connective tissue hyperplasia, and alleviation of skin inflammation, as well as the clinical application of BTX-A in treating different types of scars. However, at present there is no uniform standard for the time, method, and proportioning of BTX-A injection for scar treatment, and there is also a lack of long-term follow-up results. Further researches are needed in future to clarify the mechanism of BTX-A in inhibiting scars, establish a uniform protocol of BTX-A injection, and provide a more effective treatment plan for scars.

Indexed as

Botulinum Toxins, Type ACicatrixHumansHyperplasiaInjections, IntralesionalTreatment OutcomeBotulinum Toxins, Type A

Identifiers

PMID34404162
PMCPMC11917250
OpenAlexW3195052330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.