Evidence map›Paper›PMID 34403841›Full record

ArticleComputer methods and programs in biomedicine2021

Prediction of COVID Criticality Score with Laboratory, Clinical and CT Images using Hybrid Regression Models.

Varalakshmi Perumal, Vasumathi Narayanan, Sakthi Jaya Sundar Rajasekar

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Article in Computer methods and programs in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Varalakshmi PerumalDepartment of Computer Technology, Madras Institute of Technology, Anna University, Chennai, India. Electronic address: varanip@gmail.com.
Vasumathi NarayananDepartment of Computer Technology, Madras Institute of Technology, Anna University, Chennai, India. Electronic address: vasumathi.n29@gmail.com.
Sakthi Jaya Sundar RajasekarMelmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur, India. Electronic address: drsakthi03@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveRapid and precise diagnosis of COVID-19 is very critical in hotspot regions. The main aim of this proposed work is to investigate the baseline, laboratory and CT features of COVID-19 affected patients of two groups (Early and Critical stages). The detection model for COVID-19 is built depending upon the manifestations that define the severity of the disease.

methodsThe CT scan images are fed into the various deep learning, machine learning and hybrid learning models to mine the necessary features and predict CT Score. The predicted CT score along with other clinical, laboratory and CT scan image features are then passed to train the various Regression models for predicting the COVID Criticality (CC) Score. These baseline, laboratory and CT features of COVID-19 are reduced using Statistical analysis and Univariate logistic regression analysis.

resultsWhen analysing the prediction of CT scores using images alone, AlexNet+Lasso yields better outcome with regression score of 0.9643 and RMSE of 0.0023 when compared with Decision tree (RMSE of 0.0034; Regression score of 0.9578) and GRU (RMSE of 0.1253; regression score of 0.9323). When analysing the prediction of CC scores using CT scores and other baseline, laboratory and CT features, VGG-16+Linear Regression yields better results with regression score of 0.9911 and RMSE of 0.0002 when compared with Linear SVR (RMSE of 0.0006; Regression score of 0.9911) and LSTM (RMSE of 0.0005; Regression score of 0.9877). The correlation analysis is performed to identify the significance of utilizing other features in prediction of CC Score. The correlation coefficient of CT scores with actual value is 0.93 and 0.92 for Early stage group and Critical stage group respectively. The correlation coefficient of CC scores with actual value is 0.96 for Early stage group and 0.95 for Critical stage group.The classification of COVID-19 patients are carried out with the help of predicted CC Scores.

conclusionsThis proposed work is carried out in the motive of helping radiologists in faster categorization of COVID patients as Early or Severe staged using CC Scores. The automated prediction of COVID Criticality Score using our diagnostic model can help radiologists and physicians save time for carrying out further treatment and procedures.

Indexed as

COVID-19LaboratoriesHumansMachine LearningSARS-CoV-2Tomography, X-Ray ComputedChest CT imagesClinical featuresConvolutional neural network (CNN)COVID Criticality scoreLaboratory featuresRegression models

Identifiers

PMID34403841
PMCPMC8352851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.