Evidence map›Paper›PMID 34403334›Full record

ArticleeLife2021

Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification.

Ka-Cheuk Liu, Alethia Villasenor, Maria Bertuzzi, Nicole Schmitner, Niki Radros, Linn Rautio, Kenny Mattonet, Ryota L Matsuoka, Sven Reischauer, Didier Yr Stainier and 1 more

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Science advances · 2024
    Article
  2. Article
  3. bioRxiv : the preprint server for biology · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ka-Cheuk LiuDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6082-8801
Alethia VillasenorDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Maria BertuzziDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Nicole SchmitnerDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Niki RadrosDermatology and Venereology Division, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden.
Linn RautioDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Kenny MattonetDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0002-9705-8086
Ryota L MatsuokaDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0001-6214-2889
Sven ReischauerDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0002-6955-9481
Didier Yr StainierDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0002-0382-0026
Olov AnderssonDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6715-781X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into the avascular

Indexed as

Cell DifferentiationRegenerationAnimalsEndotheliumInsulinsInsulin-Secreting CellsMesodermZebrafishInsulinsbeta-cell regenerationcellular origindevelopmental biologydifferentiationectopic beta-cellsregenerative medicinestem cellszebrafish

Identifiers

PMID34403334
PMCPMC8370765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.