Evidence map›Paper›PMID 34403298›Full record

ArticleAutophagy2022

Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in

Liyuan Wang, Chuchu Zhao, Tao Zheng, Yi Zhang, Hanruo Liu, Xi Wang, Xianling Tang, Baowen Zhao, Ping Liu

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liyuan WangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID 0000-0001-5273-5197
Chuchu ZhaoDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID 0000-0001-5703-9246
Tao ZhengDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID 0000-0002-1820-1762
Yi ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hanruo LiuThe Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Xi WangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xianling TangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Baowen ZhaoDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Ping LiuDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Harbin Medical University · CNBeijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiel-Behnke corneal dystrophy (TBCD) is an epithelial-stromal

Indexed as

Cathepsin DCorneal Dystrophies, HereditaryAdenosine TriphosphateAnimalsAutophagyBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBlood ProteinsHEK293 CellsHumansLysosomesMiceMicrotubule-Associated ProteinsMutant ProteinsProteomicsTOR Serine-Threonine KinasesTransforming Growth Factor betaAdenosine TriphosphateBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBlood ProteinsCathepsin DMicrotubule-Associated ProteinsMutant ProteinsTBCD protein, humanTFEB protein, humantorinTOR Serine-Threonine KinasesTransforming Growth Factor betaAutophagylysosome dysfunctionTBCDTFEBTGFBItorin 1

Identifiers

PMID34403298
PMCPMC9037417
OpenAlexW3194588702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.