Evidence map›Paper›PMID 34403098›Full record

ArticleCurrent medical science2021

Obstructive Sleep Apnea Syndrome Phenotyping by Cluster Analysis: Typical Sleepy, Obese Middle-aged Men with Desaturating Events are A Minority of Patients in A Multi-ethnic Cohort of 33% Women.

Chloé Van Overstraeten, Fabio Andreozzi, Sidali Ben Youssef, Ionela Bold, Sarah Carlier, Alexia Gruwez, Anne-Violette Bruyneel, Marie Bruyneel

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Article in Current medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chloé Van OverstraetenDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Fabio AndreozziDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Sidali Ben YoussefDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Ionela BoldDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Sarah CarlierDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Alexia GruwezDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium.
Anne-Violette BruyneelResearch Department, KiCarre, Lentilly, 69210, France.
Marie BruyneelDepartment of Pulmonary Medicine, Saint-Pierre University Hospital, Université Libre de Bruxelles, Brussels, 1000, Belgium. Marie_Bruyneel@stpierrebru.be.
Université Libre de Bruxelles · BECentre Hospitalier Universitaire de Saint-Pierre · BEUniversité Le Havre Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSeveral clinical obstructive sleep apnea syndrome (OSAS) phenotypes associated with heterogeneous cardiovascular risk profiles have been recently identified. The purpose of this study was to identify clusters amongst these profiles that allow for the differentiation of patients.

methodsThis retrospective study included all moderate-to-severe OSAS patients referred to the sleep unit over a 5-year period. Demographic, symptom, comorbidity, polysomnographic, and continuous positive airway pressure (CPAP) adherence data were collected. Statistical analyses were performed to identify clusters of patients.

resultsA total of 567 patients were included (67% men, 54±13 years, body mass index: 32±7 kg/m

conclusionThis study highlights that the typical sleepy obese middle-aged men with desaturating events represent only a minority of patients in our multi-ethnic moderate-to-severe OSAS cohort of 33% females.

Indexed as

Continuous Positive Airway PressureAdultAgedBody Mass IndexCluster AnalysisFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedObesityPhenotypePolysomnographySeverity of Illness IndexSleep Apnea, ObstructiveSleepinesscardiovascular riskcluster analysiscontinuous positive airway pressureobstructive sleep apnea syndromepolysomnographysleep disturbance

Identifiers

PMID34403098
OpenAlexW3195118700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.