Evidence map›Paper›PMID 34402948›Full record

ArticleAbdominal radiology (New York)2021

Diagnostic performance of

Verena Plodeck, Ivan Platzek, Johannes Streitzig, Heiner Nebelung, Sophia Blum, Jens-Peter Kühn, Ralf-Thorsten Hoffmann, Michael Laniado, Enrico Michler, Sebastian Hoberück and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic performance of [European journal of nuclear medicine and molecular imaging · 2022
    Pooled it
  3. Article
  4. Review
  5. Radiotherapy volume delineation based on MRI andAbdominal radiology (New York) · 2025
    Article
  6. Article
  7. Article
  8. PET/MRI in colorectal and anal cancers: an update.Abdominal radiology (New York) · 2023
    Review
  9. Local Recurrences in Rectal Cancer: MRI vs. CT.Diagnostics (Basel, Switzerland) · 2023
    Review
  10. Review
  11. Radiomic Features from Post-OperativeJournal of clinical medicine · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Verena PlodeckDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany. verena.plodeck@uniklinikum-dresden.de.ORCID http://orcid.org/0000-0001-5061-9643
Ivan PlatzekDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Johannes StreitzigDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Heiner NebelungDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Sophia BlumDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Jens-Peter KühnDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Ralf-Thorsten HoffmannDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Michael LaniadoDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Enrico MichlerDepartment of Nuclear Medicine, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Sebastian HoberückDepartment of Nuclear Medicine, Helios Hospital Erfurt, Nordhäuser Strasse 74, 99089, Erfurt, Germany.
Klaus ZöphelDepartment of Nuclear Medicine, Chemnitz Hospital GmbH, Flemmingstrasse 2, 09116, Chemnitz, Germany.
Jörg KotzerkeDepartment of Nuclear Medicine, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Johannes FritzmannDepartment of General, Thoracic and Vascular Surgery, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Jürgen WeitzDepartment of General, Thoracic and Vascular Surgery, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Christoph G RadosaDepartment of Radiology, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.
Technische Universität Dresden · DEHelios Klinikum Erfurt · DEKlinikum Chemnitz · DEKlinik und Poliklinik für Psychotherapie und Psychosomatik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the diagnostic performance of

methodsAll PET/MRIs of patients in the follow-up of rectal cancer performed between 2011 and 2018 at our institution were retrospectively reviewed. Recurrence was confirmed/excluded either by histopathology or imaging follow-up (> 4 months). Four groups of readers (groups 1/2: one radiologist each, groups 3/4: one radiologist/one nuclear medicine physician) independently interpreted MRI and PET/MRI. The likelihood of recurrence was scored on a 5-point-scale. Inter-reader agreement, sensitivity, specificity, PPV/NPV and accuracy were assessed. ROC curve analyses were performed.

resultsFourty-one PET/MRIs of 40 patients (mean 61 years ± 10.9; 11 women, 29 men) were included. Sensitivity of PET/MRI in detecting recurrence was 94%, specificity 88%, PPV/NPV 97% and 78%, accuracy 93%. Sensitivity of MRI was 88%, specificity 75%, PPV/NPV 94% and 60%, accuracy 85%. ROC curve analyses showed an AUC of 0.97 for PET/MRI and 0.92 for MRI, but the difference was not statistically significant (p = 0.116). On MRI more cases were scored as equivocal (12% versus 5%). Inter-reader agreement was substantial for PET/MRI and MRI (0.723 and 0.656, respectively).

conclusion

Indexed as

Fluorodeoxyglucose F18Rectal NeoplasmsFemaleHumansMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesSensitivity and SpecificityFluorodeoxyglucose F18Radiopharmaceuticals18F-FDG-PET/MRIMRIRectal cancerRecurrence

Identifiers

PMID34402948
PMCPMC8502129
OpenAlexW3193711871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.