Evidence map›Paper›PMID 34402936›Full record

ReviewDer Nervenarzt2021

[Interactions between the brain and heart].

Sarah Deking, Jan Liman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah DekingKlinik für Neurologie, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Deutschland.
Jan LimanKlinik für Neurologie, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Deutschland. jan.liman@med.uni-goettingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain and heart are closely interconnected. Physiologically, the brain influences the way the heart beats. An example for this physiological influence is the control of the heart rate via efferences of the autonomic nervous system. Clinical examples for this direction of interactions include cardiac complications after stroke as well as takotsubo cardiomyopathy; however, the heart and brain are reciprocally connected so that heart activity also influences the brain beyond its function as the generator of bloodflow supplying the brain. Examples for this are the perception of stimuli depending on the time of presentation during the heart cycle. Clinical examples of the direction of this interaction constitute stroke as a thromboembolic complication of atrial fibrillation as well as the correlation of atrial fibrillation and dementia. This review article gives an overview of the bidirectional interactions between the heart and brain, partly including the cardiovascular system, discusses their implications for the clinical routine and gives an outlook on current fields of research.

Indexed as

Atrial FibrillationStrokeAutonomic Nervous SystemBrainHeart RateHumansCardiovascular systemCentral autonomic networkHeart beat evoked potentialMechanisms of dementiaTakotsubo

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.