Evidence map›Paper›PMID 34402927›Full record

SynthesisClinical research in cardiology : official journal of the German Cardiac Society2022

Short- and long-term outcomes after heart transplantation in cardiac sarcoidosis and giant-cell myocarditis: a systematic review and meta-analysis.

Emanuele Bobbio, Marie Björkenstam, Bright I Nwaru, Francesco Giallauria, Eva Hessman, Niklas Bergh, Christian L Polte, Jukka Lehtonen, Kristjan Karason, Entela Bollano

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical research in cardiology : official journal of the German Cardiac Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Redefining Cardiac Sarcoidosis with Advanced Imaging and Therapeutic Strategies.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Cardiac sarcoidosis recurrence post-heart transplant: A critical literature and case report.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Role of Endomyocardial Biopsy in Diagnostics of Myocarditis.Diagnostics (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Emanuele BobbioDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-8287-2448
Marie BjörkenstamDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Bright I NwaruKrefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Francesco GiallauriaDepartment of Translational Medical Sciences, 'Federico II' University of Naples, Naples, Italy.
Eva HessmanBiomedical Library, Gothenburg University Library, University of Gothenburg, Gothenburg, Sweden.
Niklas BerghDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Christian L PolteInstitute of Medicine At Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jukka LehtonenHeart and Lung Centre, Helsinki University and Helsinki University Hospital, Helsinki, Finland.
Kristjan KarasonDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Entela BollanoDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden. emanuele.bobbio@vgregion.se.
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SEHelsinki University Hospital · FI

Funding

Swedish federal government ALFGBG-932636, ALFGBG-775351, ALFGBG-633141
6 · The paper itself

Abstract

Heart transplantation (HTx) is a valid therapeutic option for end-stage heart failure secondary to cardiac sarcoidosis (CS) or giant-cell myocarditis (GCM). However, post-HTx outcomes in patients with inflammatory cardiomyopathy (ICM) have been poorly investigated. We searched PubMed, Scopus, Science Citation Index, EMBASE, and Google Scholar, screened the gray literature, and contacted experts in the field. We included studies comparing post-HTx survival, acute cellular rejection, and disease recurrence in patients with and without ICM. Data were synthesized by a random-effects meta-analysis. We screened 11,933 articles, of which 14 were considered eligible. In a pooled analysis, post-HTx survival was higher in CS than non-CS patients after 1 year (risk ratio [RR] 0.88, 95% confidence interval [CI] 0.60-1.17; I

Indexed as

Heart TransplantationCardiomyopathiesFemaleHumansMaleMiddle AgedMyocarditisSarcoidosisTimeTreatment OutcomeCardiac sarcoidosisGiant-cell myocarditisHeart transplantationInflammatory cardiomyopathyMeta-analysisSystematic review

Identifiers

PMID34402927
PMCPMC8816313
OpenAlexW3195044181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.