Evidence map›Paper›PMID 34402922›Full record

Observational studyHerz2022

Outcomes of patients with ST-segment myocardial infarction admitted during the COVID-19 pandemic : A prospective, observational study from a tertiary care center in Germany.

M Rattka, C Winsauer, L Stuhler, K Thiessen, M Baumhardt, T Stephan, W Rottbauer, A Imhof

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in Herz, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

M RattkaDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany. Manuel.Rattka@uniklinik-ulm.de.ORCID http://orcid.org/0000-0002-3269-3871
C WinsauerDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
L StuhlerDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
K ThiessenDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
M BaumhardtDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
T StephanDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
W RottbauerDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany.
A ImhofDepartment of Cardiology, Ulm University Medical Centre, Albert Einstein Allee 23, 89081, Ulm, Germany. armin.imhof@uniklinik-ulm.de.ORCID http://orcid.org/0000-0001-7452-303X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the beginning of the SARS-CoV‑2 outbreak, healthcare professionals reported that patients admitted with ST-segment myocardial infarction (STEMI) were in worse condition compared to STEMI patients admitted before the outbreak. However, data on their outcomes are sparse.

methodsWe conducted a prospective, observational, cohort study of STEMI patients admitted during the COVID-19 pandemic from March 21, 2020 to July 31, 2020 (COVID-19 group). Clinical outcomes, 30-day mortality, and reasons potentially related to a delay in patient presentation were assessed and compared with STEMI patients admitted between November 1, 2019 and March 20, 2020 (pre-COVID-19 group).

resultsA total of 124 patients were enrolled, comprising 57 patients in the pre-COVID-19 group and 67 patients in the COVID-19 group. Significantly more patients in the COVID-19 group had a time to first medical contact of greater than 24 h. Additionally, those admitted during the pandemic had a significantly lower left ventricular ejection fraction (LVEF), worse thrombolysis in myocardial infarction (TIMI) flow, received circulatory support significantly more often, and had a significantly higher 30-day mortality. Furthermore, significantly more patients stated that "information by the media" made them hesitate to contact the emergency medical services as soon as possible.

conclusionHere, we show that STEMI patients admitted during the COVID-19 pandemic had significantly prolonged times to first medical contact, were in worse condition at admission, and had an increased 30-day mortality. Additionally, we found that "information by the media" made patients during COVID-19 hesitate to contact the emergency medical services. Consequently, public health strategies have to be developed to avoid potential excess mortality of STEMI patients during the pandemic.

Indexed as

COVID-19Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionCohort StudiesGermanyHumansPandemicsProspective StudiesSARS-CoV-2Stroke VolumeTertiary Care CentersVentricular Function, LeftEmergency medical servicesEpidemiologyMortalitySARS-CoV‑2STEMI

Identifiers

PMID34402922
PMCPMC8369437

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.