ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022
Behaviorally and environmentally induced non-24-hour sleep-wake rhythm disorder in sighted patients.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- It's Not Just Light: Assessing the Intrinsic Period of the Human Circadian Pacemaker Under Dim Light Conditions Should Include Non-Photic Influences.Journal of biological rhythms · 2025Article
- Confirmatory evidence for circadian rhythm sleep-wake disorder by positive airway pressure therapy adherence data.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state.Science advances · 2025Article
- Integrating Assessment of Circadian Rhythmicity to Improve Treatment Outcomes for Circadian Rhythm Sleep-Wake Disorders: Updates on New Treatments.Current sleep medicine reports · 2025Review
- Commentary: Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light-dark cycles in mice.Frontiers in neuroscience · 2024Article
- Non-24-hour sleep-wake rhythm disorder not driven by central circadian clock dysregulation: is it not "intrinsic"?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Toward a new nosology for non-24-hour sleep-wake rhythm disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Genetics and functional significance of the understudied methamphetamine sensitive circadian oscillator (MASCO).F1000Research · 2022Review
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
STUDY
objectivesTo determine whether there was evidence of circadian or sleep-regulatory dysfunction in sighted individuals with non-24-hour sleep-wake rhythm disorder.
methodsThree sighted individuals with signs and/or symptoms of non-24-hour sleep-wake rhythm disorder were studied. Thirty-five- to 332-day laboratory and home-based assessments of sleep-wake and circadian timing, endogenous circadian period, photic input to the circadian pacemaker, and/or circadian and sleep-wake-dependent regulation of sleep were conducted.
resultsNo evidence of circadian dysfunction was found in these individuals. Instead, sleep-wake timing appeared to dissociate from the circadian timing system, and/or self-selected sleep-wake and associated light/dark timing shifted the circadian pacemaker later, rather than the circadian pacemaker determining sleep-wake timing.
conclusionsThese findings suggest that the etiology of this disorder may be light- and/or behaviorally induced in some sighted people, which has implications for the successful treatment of this disorder. CITATION: Emens JS, St Hilaire MA, Klerman EB, et al. Behaviorally and environmentally induced non-24-hour sleep-wake rhythm disorder in sighted patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.