Evidence map›Paper›PMID 34402766›Full record

ArticleGlobal health action2021

How does HIV testing modality impact the cascade of care among persons diagnosed with HIV in Ethiopia?

Malin Johansson, Clara Penno, Niclas Winqvist, Fregenet Tesfaye, Per Björkman

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Malin JohanssonClinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Clara PennoClinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Niclas WinqvistClinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Fregenet TesfayeClinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Per BjörkmanClinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.ORCID 0000-0002-3697-9375
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite scaling up of HIV programmes in sub-Saharan Africa, many people living with HIV (PLHIV) are unaware of their HIV status. New testing modalities, such as community-based testing, can improve test uptake, but it is uncertain whether type of testing modality affects the subsequent cascade of HIV care.

objectiveTo compare linkage to care and antiretroviral treatment (ART) outcomes with regard to type of HIV testing modality.

methodsA retrospective registry-based study was conducted at public ART clinics in an urban uptake area in Central Ethiopia. Persons aged ≥15 years newly diagnosed with HIV in 2015-2018 were eligible for inclusion. Data on patient characteristics and testing modality were analysed for associations with the following outcomes: ART initiation, retention in care at 12 months after starting ART, and viral suppression (<1000 copies/ml, recorded during the first 12 months after ART initiation), using uni- and multivariable analysis. Separate analyses disaggregated by sex were performed.

resultsAmong 2885 included PLHIV (median age 32 years, 59% female), 2476 (86%) started ART, 1422/2043 (70%) were retained in care, and 953/1046 (92%) achieved viral suppression. Rates of ART initiation were lower among persons diagnosed through community-based testing (adjusted odds ratio [AOR] 0.44, 95% confidence interval [CI] 0.29-0.66) and among persons diagnosed through provider-initiated testing (AOR 0.65, 95% CI 0.44-0.97) compared with facility-based voluntary counselling and testing. In sex-disaggregated analyses, community-based testing was associated with lower rates of ART initiation among both women and men (AOR 0.47, 95% CI 0.27-0.82; AOR 0.39, 95% CI 0.19-0.78, respectively). No differences were found for retention in care or viral suppression with regard to test modality.

conclusionType of HIV testing modality was associated with likelihood of ART initiation, but not with subsequent treatment outcomes among persons starting ART.

Indexed as

HIV InfectionsHIV TestingAdultAnti-Retroviral AgentsEthiopiaFemaleHumansMaleRetrospective StudiesAnti-Retroviral Agentscascade of carecommunity-based testingEthiopiaHIVtest modality

Identifiers

PMID34402766
PMCPMC8381907
OpenAlexW3193708625

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.