ArticlemSystems2021
Elucidating the Beta-Diversity of the Microbiome: from Global Alignment to Local Alignment.
Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gut Microbiota Alterations Associated With Colonization by Multidrug-Resistant Organisms in ICU Patients: First Systematic Review and Meta-Analysis.MicrobiologyOpen · 2026Pooled it
- The Role of the Gut Microbiota in the Development and Progression of Major Depressive and Bipolar Disorder.Nutrients · 2021Pooled it
- Mild concussion impairs extinction of avoidance and alters respective brain circuits in male rats.Experimental neurology · 2026Article
- Screening and dynamic change study of microbial and metabolite markers for calf diarrhea based on multi-omics and machine learning.mSystems · 2026Article
- Liraglutide Modifies Gut Microbiota Without Modulating Doxorubicin-Induced Toxicity in Rats.Antioxidants (Basel, Switzerland) · 2026Article
- Epithelial remodeling and microbial dysbiosis in the lower respiratory tract of vitamin A-deficient mouse lungs.Scientific reports · 2026Article
- ResMicroDb: a comprehensive database and analysis platform for the human respiratory microbiome.Nucleic acids research · 2026Article
- Gut microbiota dysbiosis in adolescent depression: a comparative analysis with adult depression and healthy adolescent.Frontiers in microbiology · 2026Article
- Unlocking the potential of willow condensed tannins: effects on rumen fermentation, microbiome, and metabolome for sustainable ruminant nutrition.Animal microbiome · 2025Article
- Impact of Blastocystis carriage and colonization intensity on gut microbiota composition in a non-westernized rural population from Colombia.PLoS neglected tropical diseases · 2025Article
- Functional redundancy and niche specialization in honeybee and Varroa microbiomes.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Fermented Kamut Wheat Diet Prevents DSS-Induced Colitis via Modulating Gut Microbiota in Mice.International journal of molecular sciences · 2025Article
- Key features and guidelines for the application of microbial alpha diversity metrics.Scientific reports · 2025Article
- Article
- Nutraceutical supplement slim reshaped colon histomorphology and reducesFrontiers in microbiology · 2025Article
- Differential impact ofHeliyon · 2024Article
- Gut Microbiota and Metabolic Alterations Associated with Heart Failure and Coronary Artery Disease.International journal of molecular sciences · 2024Article
- Gut Microbes Associated with Neurodegenerative Disorders: A Comprehensive Review of the Literature.Microorganisms · 2024Review
- Gulf War Illness Is Associated with Host Gut Microbiome Dysbiosis and Is Linked to Altered Species Abundance in Veterans from the BBRAIN Cohort.International journal of environmental research and public health · 2024Article
- Characterization of the gut microbiota and fecal metabolome in the osteosarcoma mouse model.Aging · 2024Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Quantitative comparison among microbiomes can link microbial beta-diversity to environmental features, thus enabling prediction of ecosystem properties or dissection of host-microbiome interaction. However, to compute beta-diversity, current methods mainly employ the entire community profiles of taxa or functions, which can miss the subtle differences caused by low-abundance community members that may play crucial roles in the properties of interest. In this work, I review the distance metrics and search engines that we developed to match microbiomes at a large scale based on whole-community-level similarities, as well as their limitations in tackling the microbiome changes caused by less abundant community features. Then I propose the concept of microbiome "local alignment," including an algorithm to measure microbiome similarity on specific fractions of biodiversity and an indexing strategy for rapidly fetching microbiome local-alignment matches from the data repository.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.