Evidence map›Paper›PMID 34402579›Full record

ArticleJournal of applied clinical medical physics2021

Trend analysis of the dosimetric impact of anatomical changes during proton therapy for maxillary sinus carcinoma.

Yuki Narita, Takahiro Kato, Takashi Ono, Sho Oyama, Yuhei Yamazaki, Hisao Ouchi, Kimihiro Takemasa, Masao Murakami

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuki NaritaDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.ORCID https://orcid.org/0000-0001-7594-6376
Takahiro KatoDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Takashi OnoDepartment of Radiation Oncology, Faculty of Medicine, Yamagata University, Yamagata, Japan.
Sho OyamaDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Yuhei YamazakiDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Hisao OuchiDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Kimihiro TakemasaDepartment of Radiation Physics and Technology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Masao MurakamiDepartment of Radiation Oncology, Southern TOHOKU Proton Therapy Center, Koriyama, Japan.
Southern Tohoku General Hospital · JPFukushima Medical University · JPYamagata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnatomical changes, such as shrinkage and aeration, can affect dose distribution in proton therapy (PT) for maxillary sinus carcinoma (MSC). These changes can affect the dose to the target and organs at risk (OARs); however, when these changes occur during PT is unclear. This study aimed to investigate the dosimetric impact of anatomical changes during PT. MATERIALS AND

methodsFifteen patients with MSC were enrolled in this study. Initial PT plans were generated based on initial computed tomography (CT) images. Several repeat CT images were obtained to confirm anatomical changes during PT. Evaluation PT plans were generated by copying initial PT plans to repeat CT images. The dose differences of the target and OARs were evaluated by comparing both the plans.

resultsAt 3-4 weeks after the initiation of PT, the target volume reduced by approximately 10% as compared with the initial volume. Consequently, the target volumes gradually varied until the end of treatment. The value of V

conclusionThe trend analysis in this study showed that anatomical changes appeared 3-4 weeks after the start of PT, and the dose to the OARs tended to increase. Therefore, it is recommended to check the status of tumor 3-4 weeks after the start of treatment to avoid the deterioration of dose distribution due to these changes.

Indexed as

CarcinomaProton TherapyHumansMaxillary SinusRadiotherapy DosageRadiotherapy Planning, Computer-Assistedadaptive radiotherapyanatomical changemaxillary sinus carcinomaproton therapy

Identifiers

PMID34402579
PMCPMC8425936
OpenAlexW3195592490

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.