Evidence map›Paper›PMID 34402569›Full record

ArticleVeterinary ophthalmology2021

Labial and buccal minor salivary glands of the dog - location, three-dimensional arrangement and histology.

Simone Gabner, Christina Michels, Bernadette Lanz, Barbara Nell, Stephan Handschuh, Monika Egerbacher

Open access · bronzeAbstract read
In one paragraph

Article in Veterinary ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  5. Author Response: Concerns About a Dog Model of Dry Eye Disease.Translational vision science & technology · 2024
    Article
  6. Establishment of a Beagle Dog Model of Dry Eye Disease.Translational vision science & technology · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Simone GabnerHistology and Embryology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Austria.ORCID https://orcid.org/0000-0001-8853-5939
Christina MichelsHistology and Embryology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Austria.
Bernadette LanzHistology and Embryology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Austria.
Barbara NellDepartment of Companion Animals and Horses, University of Veterinary Medicine, Vienna, Austria.
Stephan HandschuhVetCore Facility for Research, University of Veterinary Medicine, Vienna, Austria.
Monika EgerbacherUMIT TIROL, Private University for Health Sciences, Medical Informatics and Technology GmbH, Hall in Tirol, Austria.
University of Veterinary Medicine Vienna · ATUMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTransplantation of minor salivary glands (MSGs) to the conjunctiva is a treatment option for patients suffering from dry eye disease. As there is not enough information about labial and buccal MSGs in dogs, the aim of this study was to provide evidence of the presence of these glands and to investigate their spatial arrangement and excretory ducts.

methodsThe oral mucosa of the lower lip of 4 dogs and the whole lower jaw of 1 dog were used for histological and microCT analysis. Presence, number, volumes and the tissue depth of MSGs were assessed.

resultsHistological analysis showed that compact tubulo-acinar glands were located in the submucosal connective tissue. MicroCT images revealed that 9 to 21 MSGs were arranged in a single row at the level of the dental alveolae. The volume of the MSGs increased from rostral to caudal and the total volume of glandular tissue per animal ranged from 35.01 mm

conclusionsThe location, number and volume of the labial and buccal MSGs in the dog could be detected and described using microCT scans and histology. The present results can provide valuable information for future transplantation of labial MSGs as therapeutic measure against keratoconjunctivitis sicca.

Indexed as

AnimalsDogsFemaleImage Processing, Computer-AssistedMaleMouth MucosaSalivary GlandsSalivary Glands, Minor3D reconstructionautotransplantationcaninedry eye diseasekeratoconjunctivitis siccamicroCT

Identifiers

PMID34402569
PMCPMC8596902
OpenAlexW3194686375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.