Evidence map›Paper›PMID 34402306›Full record

ArticleBone & joint open2021

Comparative effectiveness of treatment options for displaced midshaft clavicle fractures : a systematic review and network meta-analysis.

John R Martin, Patrick E Saunders, Mark Phillips, Sean M Mitchell, Michael D Mckee, Emil H Schemitsch, Niloofar Dehghan

Abstract read
In one paragraph

Article in Bone & joint open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Low-profile 2.7 mm VA-LCP plates vs. 3.5 mm LCP plates for midshaft clavicle osteosynthesis: a retrospective comparison.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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  5. Efficacy of intramedullary bridge fixation for midshaft clavicle fractures: a retrospective analysis of a novel technique.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

John R MartinDepartment of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0002-3844-7022
Patrick E SaundersDepartment of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Mark PhillipsMcMaster University, Hamilton, Ontario, Canada.
Sean M MitchellDepartment of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0002-0584-3256
Michael D MckeeDepartment of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Emil H SchemitschUniversity of Western Ontario, London, Canada.
Niloofar DehghanDepartment of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aims of this network meta-analysis (NMA) were to examine nonunion rates and functional outcomes following various operative and nonoperative treatments for displaced mid-shaft clavicle fractures.

methodsInitial search strategy incorporated MEDLINE, PubMed, Embase, and the Cochrane Library for relevant randomized controlled trials (RCTs). Four treatment arms were created: nonoperative (NO); intramedullary nailing (IMN); reconstruction plating (RP); and compression/pre-contoured plating (CP). A Bayesian NMA was conducted to compare all treatment options for outcomes of nonunion, malunion, and function using the Disabilities of the Arm Shoulder and Hand (DASH) and Constant-Murley Shoulder Outcome scores.

resultsIn all, 19 RCTs consisting of 1,783 clavicle fractures were included in the NMA. All surgical options demonstrated a significantly lower odds ratio (OR) of nonunion in comparison to nonoperative management: CP versus NO (OR 0.08; 95% confidence interval (CI) 0.04 to 0.17); IMN versus NO (OR 0.07; 95% CI 0.02 to 0.19); RP versus NO (OR 0.07; 95% CI: 0.01 to 0.24). Compression plating was the only treatment to demonstrate significantly lower DASH scores relative to NO at six weeks (mean difference -10.97; 95% CI -20.69 to 1.47).

conclusionSurgical fixation demonstrated a lower risk of nonunion compared to nonoperative management. Compression plating resulted in significantly less disability early after surgery compared to nonoperative management. These results demonstrate possible early improved functional outcomes with compression plating compared to nonoperative treatment. Surgical fixation of mid-shaft clavicle fractures with compression plating may result in quicker return to activity by rendering patients less disabled early after surgery. Cite this article:

Indexed as

Compression plateIntramedullary nailMidshaft clavicle fracturesNetwork meta-analysisNon-operativeReconstruction plate

Identifiers

PMID34402306
PMCPMC8384438

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.