Evidence map›Paper›PMID 34402120›Full record

ArticleAddiction (Abingdon, England)2022

Increase in recreational drug use between 2008 and 2018: results from a prospective cohort study among HIV-negative men who have sex with men.

Liza Coyer, Anders Boyd, Udi Davidovich, Ward P H van Bilsen, Maria Prins, Amy Matser

Open access · hybridAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Liza CoyerDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-5830-2982
Anders BoydDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-9512-8928
Udi DavidovichDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.
Ward P H van BilsenDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.
Maria PrinsDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-2967-0289
Amy MatserDepartment of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-4291-1905
GGD Amsterdam · NLStichting HIV Monitoring · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo test whether recreational drug use (RDU) and sexualized drug use (SDU) changed in the Amsterdam area between 2008 and 2018 and quantify associations of SDU with condomless anal sex (CAS), recent human immunodeficiency virus (HIV) or sexually transmitted infections (STI) among human immunodeficiency virus (HIV)-negative men who have sex with men (MSM).

designOpen prospective cohort study.

settingPublic Health Service of Amsterdam, the Netherlands.

participantsA total of 976 HIV-negative MSM, aged ≥ 18 years. MEASUREMENTS: Self-reported RDU and sexual behaviour in the past 6 months. Laboratory-confirmed HIV and STI (chlamydia, gonorrhoea and syphilis). We studied: any RDU; any SDU (i.e. any RDU during sex); specific SDU (i.e. use of mephedrone, methamphetamine, gamma-hydroxybutyric acid/gamma-butyrolactone, ketamine, amphetamine, cocaine and/or ecstasy during sex); use of individual drugs; and use of individual drugs during sex. We evaluated changes over calendar years in the proportion of individuals with these end-points [using logistic regression with generalized estimating equations (GEE)] and number of drugs (using negative binomial regression with GEE), adjusted for current age, country of birth and education level.

findingsMedian age of participants in 2008 was 33.2 years (interquartile range = 27.8-40.1); 83.1% were born in the Netherlands. The proportion of any RDU increased from 67.2% in 2008 to 69.5% in 2018 [adjusted odds ratio (aOR) = 1.25; 95% confidence interval (CI) = 1.03-1.51]. Any SDU increased from 53.8% in 2008 to 59.8% in 2013 (aOR = 1.23; 95% CI = 1.07-1.42) and remained stable afterwards. Specific SDU increased from 25.0% in 2008 to 36.1% in 2018 (aOR = 2.10; 95% CI = 1.71-2.58). The average number of drugs used increased for those reporting any RDU, any SDU and specific SDU (all P < 0.05. Among those engaging in sex, any SDU was associated with CAS (aOR = 1.36; 95% CI = 1.19-1.55), HIV (aOR = 5.86; 95% CI = 2.39-14.4) and STI (aOR = 2.31; 95% CI = 1.95-2.73). Specific SDU was associated with CAS (aOR = 1.58; 95% CI = 1.37-1.81), HIV (aOR = 6.30; 95% CI = 3.28-12.1) and STI (aOR = 2.15; 95% CI = 1.81-2.55).

conclusionsAmong human immunodeficiency virus (HIV)-negative men who have sex with men in Amsterdam, recreational drug use, including sexualized drug use, increased between 2008 and 2018. Sexualized drug use was strongly associated with condomless anal sex, HIV and sexually transmitted infections.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSexually Transmitted DiseasesSubstance-Related DisordersAdultCross-Sectional StudiesHomosexuality, MaleHumansMaleProspective StudiesRecreational Drug UseSexual BehaviorChemsexcondomless sexHIVlongitudinal analysismen who have sex with menrecreational drug usesexual behavioursexualized drug useSTI

Identifiers

PMID34402120
PMCPMC9292014
OpenAlexW3195458217

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.